Hydroxybutyrate copolyesters

Y Doi, Y Kanesawa, M Kunioka, T Saito. Biodegradation of microbial copolyesters Poly(3-hydroxybutyrate-co-3-hydroxyvalerate) and poly(3-hydroxybutyrate-co-4-hydroxybutyrate). Macromolecules 23 26-31, 1990. 

Doi, Y., Kunioka, M., Nakamura, Y., and Soga, K. 1988. Nuclear magnetic resonance studies on unusual bacterial copolyesters of 3-hydroxybutyrate and 4-hydroxybutyrate. Macromolecules, 21,2722-2727. 

The most familiar examples of copolyesters are poly-(3HB-co-3HV) and P(3HB-CO-4HB). Poly-(3HB-co-3HV) consists of (/ )-3-hydroxybutyrate (3HB) and (R)-3-hydroxyvalerate (3HV), forming an ethyl group as a side chain. Poly-(3HB-co-4HB)... 

While the first efforts [11, 12] of the biotechnological generation of aliphatic homopolyesters and random copolyesters have been restricted essentially on monomers from 3-hydroxybutyric acid (3HB) and 3-hydroxypentanic acid (3HV), newer investigations concentrate on mraiomers with branches in the range of medium chain length, the so-called thermoplastic elastomers [13—15]. Steinbiichel et al. [3] catalogued more than 100 hydroxyalkanoic acids as craistituents of biosynthetic PHAs. 

There are many kinds of bacterially synthesized copoly(hydroxyalkanoic acid)s [10]. A well-known typical copolyester is poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid), P(3HB-co-3HV),... 

Abe, H. and Doi, Y B/oraacwmo/e. 2002, 3/7/, 33- 3i. Side-Chain Effect of Second Monomer Units on Crystalline Morphology, Thermal Properties, and Enzymatic Degradability for Random Copolyesters of (R)-3-Hydroxybutyric Acid with (R)-3-Hy-droxyalkanoic Acids. 

Choi, G. G. Kim, H. W. and Rhee, Y. H. Enzymatic and non-enzymatic degradation of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) copolyesters produced by Alcalig-enes sp. MT-16. J. Microbiol 2004, 42(4), 346-352. 

Figure Poly(/3-hydroxyalkanoates) a) polyOS-hydroxybutyric acid), b) copolyester of hydroxybutyric acid and /5-hydroxyva-leric acid, c) homopolyester of hydroxyoctanoic acid.

CH2 carbons have shown the existence of two components with different Ti values for each carbon. This Ti result is in accord with the previous Ti results for poly[(R)-3-hydroxybutyric acid] [P(3HB)] homopolymer and other P(3HB)-type random copolyesters. In previous papers, however, the assignment of the two components with different Ti values have been remained unsolved. By performing variable-temperature experiments and by comparing with the results... 

Doi Y, Tamaki A, Kunioka M, Soga K (1988b) Production of copolyesters of 3-hydroxybutyrate and 3-hydroxyvalerate by Alcaligenes eutrophus from but)rric and pentanoic acids. Appl Microbiol Biotechnol 28 (4) 330-334 doi 10.1007/bf00268190 Donald PF (2004) Biodiversity impacts of some agricultural commodity production systems. Conserv Biol 18 17—38... 

Kasuya K-i, Inoue Y, Doi Y (1996) Adsorption kinetics of bacterial PHB depolymerase on the surface of polyhydroxyalkanoate films. Int J Biol Macrom 19 35 0 Kasuya K-i, Ohura T, Masuda K, Doi Y (1999) Substrate and binding specificities of bacterial polyhydroxybutyrate depolymerases. Int J Biol Macromol 24 329-336 Kato M, M. HJB, Kang CK, Fukui T, Doi Y (1996) Production of a novel copolyester of 3-hydroxybutyric acid and medium-chain-length 3-hydroxyalkanoic acids by Pseudomonas sp. 61-3 from sugars Appl Microbiol Biotechnol 45 363-370 Kaushik N, Kumar K, Kumar S, Kaushik N, Roy S (2007) Genetic variability ruid divergence studies in seed traits and oil content of Jatropha (Jatropha curcas L.) accessions. Biomass Bioenerg 31 497-502... 

Kumar A, Sharma S (2008) An evaluation of multipurpose oil seed crop for industrial uses (Jatropha curcas L.) a review. Ind Crop Prod 28 1-10 Kumar V, Rani A, Tindwani C, Jain M (2003) Lipoxygenase isozymes and trypsin inhibitor activities in soybean as influenced by growing location. Food Chem 83 79-83 Kunioka M, Kawaguchi Y, Doi Y (1989) Production of biodegradable copolyesters of 3-hydroxy-butyrate and 4-hydroxybutyrate by Alcaligenes eutrophus. Appl Microbiol Biotechnol 30 56-573... 

Qu XH, Wu Q, Liang J, Qu X, Wang SG, Chen GQ (2005) Enhanced vascular-related cellular affinity on surface modified copolyesters of 3-hydroxybutyrate and 3-hydroxyhexanoate (PHBHHx). Biomaterials 26 6991-7001... 

Other approaches to improve the properties of PHB is the production of derivatives based on PHB via the biosynthesis of copolyesters containing PHB units with other 3-hydroxyalkanoates units [19], such as poly [3-hydroxybutyrate-co-hydroxyvalerate] [PHBV] [20] or poly [3-hydroxybutyrate-co-3-hydroxyhexanoate] [21], with different molar ratios of hydroxycarboxylic acids. This approach has been investigated extensively [22] because it can... 

Figure 2.22a reports the DCI mass spectrum of a microbial copolyester, poly()3-hydroxybutyrate-co-15% )3-hydrox5rvalerate)(PFlB/HV). The relative intensities of several series of oligomers in the spectrum, from dimers to hexamers, are compared with theoretical intensities (Figure 2.22b). Each series...

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