Sulfides reaction with hydrogen peroxide

The dithiophenol derivative 315, prepared from the dinitro 314 via reduction, diazotization, and subsequent reaction with sulfide, under mild oxidative conditions, afforded the cyclic disulfide 310, which was converted into dioxide 316 with hydrogen peroxide or a peracid (Scheme 66) <2004W0099162>. The already known, dithiocin 310, obtained... 

PTN(Me) is a white microcrystalline material, which is air stable in the solid state. The corresponding oxide cannot be obtained by classical P-phosphine oxidation with hydrogen peroxide, while the sulfide and selenide derivatives are easily and quantitatively prepared by reaction with the appropriate chalcogen element.6 PTN (Me) is soluble in nonpolar and polar solvents including water. At 20°C, PTN(Me), 1.18 g dissolves in 1 mL of water (6.81 x 10 2M). 

Reaction of an alkene with ozone leads to a 1,2,3-trioxolane, which rearranges to a 1,2,4-trioxolane (an ozonide). Subsequent treatment with hydrogen peroxide or with dimethyl sulfide leads to an aldehyde, ketone, or carboxylic acid product. When an ozonide contains a C-H unit, oxidation with hydrogen peroxide leads to a carboxylic acid, but reaction with dimethyl sulfide leads to an aldehyde 51, 52, 53, 54, 78,82,83,117. 

A heterocyclic ring may be used in place of one of the benzene rings without loss of biologic activity. The first step in the synthesis of such an agent starts by Friedel-Crafts-like acylation rather than displacement. Thus, reaction of sulfenyl chloride, 222, with 2-aminothiazole (223) in the presence of acetic anhydride affords the sulfide, 224. The amine is then protected as the amide (225). Oxidation with hydrogen peroxide leads to the corresponding sulfone (226) hydrolysis followed by reduction of the nitro group then affords thiazosulfone (227). ... 

Hydrogen peroxide. Contact of H202 so In from a broken bottle with pervious packages of permanganate caused a violent reaction and fire Hydrogen trisulfide. Contact with solid permanganate ignites the liq sulfide... 

When lcad(II) sulfide is treated with hydrogen peroxide, the possible products are either lead(II) sulfate or lead(IV) oxide and sulfur dioxide, (a) Write balanced equations for the two reactions, (b) Using data available in Appendix 2A, determine which possibility is more likely. 

Figure 4-13 shows an example from a three-dimensional model simulation of the global atmospheric sulfur balance (Feichter et al, 1996). The model had a grid resolution of about 500 km in the horizontal and on average 1 km in the vertical. The chemical scheme of the model included emissions of dimethyl sulfide (DMS) from the oceans and SO2 from industrial processes and volcanoes. Atmospheric DMS is oxidized by the hydroxyl radical to form SO2, which, in turn, is further oxidized to sulfuric acid and sulfates by reaction with either hydroxyl radical in the gas phase or with hydrogen peroxide or ozone in cloud droplets. Both SO2 and aerosol sulfate are removed from the atmosphere by dry and wet deposition processes. The reasonable agreement between the simulated and observed wet deposition of sulfate indicates that the most important processes affecting the atmospheric sulfur balance have been adequately treated in the model. 

Peroxides are cleaved to 2 mol of alcohols by L1A1H4 or by catalytic hydrogenation. Peroxides can be reduced to ethers with P(OEt)3. ° In a similar reaction, disulfides (RSSR ) can be converted to sulfides (RSR ) by treatment with tris(diethylamino)phosphine, (Et2N)3P. ... 

Tertiary phosphine sulfides are generally stable compounds and are not easily oxidised by air, although they can be oxidised by hydrogen peroxide or dilute nitric acid. The analogous tertiary phosphine selenides and tellurides are however, more reactive to oxidation. Similar to the sulfides they can be prepared from the direct reaction of elemental chalcogen with a tertiary phosphine (Equation 1). Tertiary phosphine selenides are also accessible from tertiary phosphines using KSeCN as the selenium source instead of the element itself. 

Oxidation of the fused thiazine 192 by hydrogen peroxide yielded the cyclic sulfone 193 <2004T4361>. Oxidation of the fused thiazaphosphole 195 was accomplished by /-butyl peroxide to yield 196 in relatively low yield (33%), whereas reaction of 194 with elemental sulfur yielded the P-sulfide 195 in 62% yield <1994PS59>. 

Thiadiazole sulfides are readily oxidised to the corresponding sulfoxides and sulfones. For example, the sulfide (139) is converted into the sulfoxide (140) (Equation (19)) using m-chloroperbenzoic acid <84CHEC-I(6)463> and reaction of the 5-methylthio derivative (137) (R = Ph) with hydrogen peroxide in acetic acid gives the sulfone (141) (R = Ph) (Equation (20)) (89MI 408-0l>. 

Earlier it was reported that hydrogen peroxide and cumene hydroperoxide improve the yields of 1,3-diarylureas from the reaction of weakly basic aromatic amines with carbonyl sulfide at elevated temperatures [80]. The results are summarized in Table X. 

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