Hydrogen peroxide chemically modified

A. Eftekhari, Aluminum electrode modified with manganese hexacyanoferrate as a chemical sensor for hydrogen peroxide. Talanta 55, 395 402 (2001). 

M.S. Lin and B.I. Jan, Determination of hydrogen peroxide by utilizing a cobalt(II)hexacyanoferrate-modified glassy carbon electrode as a chemical sensor. Electroanalysis 9, 340-344 (1997). 

Fig. 18b.9. Example cychc voltammograms due to (a) multi-electron transfer redox reaction two-step reduction of methyl viologen MV2++e = MV++e = MV. (b) ferrocene confined as covalently attached surface-modified electroactive species—peaks show no diffusion tail, (c) follow-up chemical reaction A and C are electroactive, C is produced from B through irreversible chemical conversion of B, and (d) electrocatalysis of hydrogen peroxide decomposition by phosphomolybdic acid adsorbed on a graphite electrode.

The production of industrially important perfluoroalkane sulfonic acids is generally accomplished by electrochemical fluorination. This method of preparation remains expensive and proceeds in good yields only for short hydrocarbon chains.30 Recently however, Wakselman and Tordeux have described a chemical method for the preparation of trifluoromethane sulfonic acid.31 The procedure involves reaction of a metal selected from zinc, cadmium, manganese, and aluminum with sulfur dioxide in DMF, followed by the introduction of trifluoromethyl bromide under slight pressure. The intermediate sulfinate is subsequently oxidized by hydrogen peroxide, and then hydrolyzed which leads to formation of the trifluoromethane sulfonic acid. Successful extension of the sulfination process to the modification of PCTFE should result in the formation of a sulfinated polymer which can ultimately be oxidized to give a sulfonic-acid modified polymer. 

In the synthesis of vitamin C, the oxidation of diacetone L-sorbose to diacetone 2-keto-L-gulonic acid proceeds at an Ni-anode in the presence of hydroxide. Under these conditions, the nickel hydroxide surface is anodically transformed to NiOOH, the nickel peroxide, which acts as chemical oxidant via hydrogen atom abstraction. Thus, a chemically modified redox-active electrode acts as a heterogeneous redox catalyst [13] ... 

The sulfur atom of methionine residues may be modified by formation of sulfonium salts or by oxidation to sulfoxides or the sulfone. The cyanosulfonium salt is not particularly useful for chemical modification studies because of the tendency for cyclization and chain cleavage (129). This fact, of course, makes it very useful in sequence work. Normally, the methionine residues of RNase can only be modified after denaturation of the protein, i.e., in acid pH, urea, detergents, etc. On treatment with iodoacetate or hydrogen peroxide, derivatives with more than one sulfonium or sulfoxide group did not form active enzymes on removal of the denaturing agent (130) [see, however, Jori et al. (131)]. There was an indication of some active monosubstituted derivatives (130, 132). 

M.A.T. Gilmartin, R.J. Ewen, J.P. Hart and C.L. Honeybourne, Volt-ammetric and photoelectron spectral elucidation of the electrocatalytic oxidation of hydrogen-peroxide at screen-printed carbon electrodes chemically-modified with cobalt phthalocyanine, Electroanalysis, 7 (1995) 547-555. 

Preparation of Prussian blue-modified screen-printed electrodes via a chemical deposition for mass production of stable hydrogen peroxide sensors... 

T. Sakamoto, C. Pac, Selective epoxidation of olefins by hydrogen peroxide in water using a polyoxometalate catalyst supported on chemically modified hydrophobic mesoporous silica gel. Tetrahedron Lett. 41 (2000) 10009. 

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