Hydrazines ethylene derivatives

Reactions of azides with hydrazine Ethylene derivatives from 1,2-azidosulfonates... 

Polyherbicide derivatives based on PMMA resins were prepared by the reactions of crosslinked PMMA (2 % DVB) with hydrazine, ethylene- and hexamethylene diamine followed by modification with the acid chlorides of 2,4-D and CMPA (Scheme 3.8). The effect of the polymer stracture and pH of the aqueous environment on hydrolysis rates were investigated [133],... 

Reaction of sodium hydrazide with ethylene derivatives Addition and hydrazinolysis Hydrazines, hydrazones, and hydrocarbons ... 

Curtius degradation 16, 560 enamines 16, 65 ethylene derivatives by reductoamination, ozonolytic 18, 530 ethyleneketones 18, 465 hydrazines s. N-Deamina-tion... 

Fig. 6. Key intermediates derived from benzene. The alkylation reaction shown employs ethylene oxide. Hydrazine condenses with acetoacetic acid to form...

However, when the reaction was carried out in a mixture of ethylene glycol and toluene and followed by hydrolysis the 2-keto derivative 42 was obtained in 54% yield, presumably via the more stable ene-hydrazine intermediate 41. 

Types of compounds are arranged according to the following system hydrocarbons and basic heterocycles hydroxy compounds and their ethers mercapto compounds, sulfides, disulfides, sulfoxides and sulfones, sulfenic, sulfinic and sulfonic acids and their derivatives amines, hydroxylamines, hydrazines, hydrazo and azo compounds carbonyl compounds and their functional derivatives carboxylic acids and their functional derivatives and organometallics. In each chapter, halogen, nitroso, nitro, diazo and azido compounds follow the parent compounds as their substitution derivatives. More detail is indicated in the table of contents. In polyfunctional derivatives reduction of a particular function is mentioned in the place of the highest functionality. Reduction of acrylic acid, for example, is described in the chapter on acids rather than functionalized ethylene, and reduction of ethyl acetoacetate is discussed in the chapter on esters rather than in the chapter on ketones. 

Another important example is the addition of alkene oxides, say ethylene oxide, to compounds of the proton donor class such as amines, alcohols, water, and hydrazine to form monoalkoxy, dialkoxy, trialkoxy, etc., derivatives, some examples of which are shown below ... 

A sensor for organic chloride-containing compounds was constructed by immobilization of luminol or tris (2,2 bipyridyl) ruthenium (III) between a PMT and a poly (tetrafluoro) ethylene (PTFE) membrane [15], through which a stream of air was sampled by diffusion. A heated Pt filament incorporated in the gas line leading to the CL cell was used to oxidize the analytes prior to diffusion across the PTFE membrane. Detection limits for CC14, CHC13, and CH2C12 were 1.2-4 ppm. A similar device could also be used for the determination of hydrazine and its monomethyl and dimethyl derivatives or NH3 vapor. The detection limit for hydrazine was only 0.42 ppb [16]. 

Dihydropyridazines are obtained from 1,4-dicarbonyl compounds and hydrazine (Section III,B) or from the reaction of sym-tetrazines and simple ethylenic compounds (Section III,H). There are also a few special reactions, such as that between a tetrahydrofuran and phenylhydrazine, or from a 1,4,5,6-tetrahydropyridazine derivative. The 1,4-dihydro structure has been found to be correct, rather than the 1,6-dihydro structure, postulated earlier for some of these reduced pyridazines (Section III,H). 1,4-Dihydropyridazines can be reduced or oxidized easily and acid treatment of l-tosyl-1,4-dihydropyridazine causes rearrangement to 1-tosylaminopyrrole. ... 

The base-catalyzed additions of glyoxal to formamide and methanesulfonamide afforded 1,4-diformyl- (895, 1663) and l,4-bis(methylsulfonyl) derivatives (895) of 2,3,5,6-tetrahydroxypiperazines, respectively, in addition to the corresponding A iV -disubstituted 1,2-diamino-l, 2-ethanediols (895). Salts of 2,3,5,6-tetrahydroxy-piperazine-l,4-disulfonic acid were similarly prepared by the addition of aqueous glyoxal to sulfamic acid in the presence of base (1664). Ethylene dichloride with hydrazine in ethanol gave ethylene dihydrazine, 1,4-diaminopiperazine, and poly(ethylenehydrazine) (1665). 

Deoxygenation of the carbonyl group of aldehydes and ketones via the intermediacy of their hydrazone derivatives, known as the Wolff-Kishner reduction,offers an alternative to the thioacetal desulfurization method. The Wolff-Kishner reduction in the presence of hydrazine and NaOH (or KOH) has been replaced largely by the Huang-Minlon method,where the deoxygenation is carried out with hydrazine in refluxing ethylene glycol. 

A method of almost universal applicability for the deoxygenation of carbonyl compounds is the Wolff-Kishner reduction While the earlier reductions were carried out in two steps on the derived hydrazone or semicarbazone derivatives, the Huang-Minlon modification is a single-pot operation. In this procedure, the carbonyl compound and hydrazine (hydrate or anhydrous) are heated (180-220 °C) in the presence of a base and a proton source. Sodium or potassium hydroxide, potassium-t-butoxide and other alkoxides are the frequently used bases and ethylene glycol or its oligomers are used as the solvent and proton source. Over the years, several modifications of this procedure have been used to cater to the specific needs of a given substrate. The Wolff-Kishner reaction works well with both aldehydes and ketones and remains the most routinely used procedure for the preparation of alkanes from carbonyl compounds (Table 9). This method is equally suitable for the synthesis of polycyclic and hindered alkanes. 

Zalipsky S, Menon-Rudolph Hydrazine S (1998) Derivatives Of poly(ethylene glycol) and their conjugates. In Harris JM (ed) Poly(ethylene glycol) chemistry biotechni-cal and biomedical applications, 2nd edn. Plenum, New York, p 319... 

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