Human whole blood culture system

CHRONIC HEALTH RISKS a rubber solvent induced chromosomal aberrations in human whole-blood cultures repeated exposure can damage the nervous system, including headache, fatigue, poor concentration, emotional instability, impaired memory and other intellectual functions chronic neruotoxic effects include motor polyneuropathy prolonged contact can cause drying and cracking of skin. 

The method has been applied to many biological systems perfused heart, lung and vascular tissue, arterial and venous blood, culture fluids from various cells (from endothelium, blood, bone, thymus) and blood platelets. The influence of diet (different poly-unsaturated fatty acids, e.g. n-6 versus n-3), medicines (aspirin) and drugs (nicotine) was studied. We could not detect any prostacyclin (< 20 pg/ml) in whole human blood obtained during diagnostic catherization of the arteries and... 

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