Human immunodeficiency virus chemokine coreceptors

Brelot A, Heveker N, Montes M, Alizon M. Identification of residues of CXCR4 critical for human immunodeficiency virus coreceptor and chemokine receptor activities. J Biol Chem 2000 275(31) 23736-23744. 

Ayehunie S, Garcia-Zepeda EA, Hoxie JA, et al. Human immunodeficiency virus-1 entry into purified blood dendritic cells through CC and CXC chemokine coreceptors. Blood 1997 90(4) 1379-1386. 

In the last decade it has become apparent that the human immunodeficiency virus (HIV) uses endogenous chemokine receptors, in particular CXCR4 and CCR5, as coreceptors for cell entry (Fauci, 1996). The Duffy antigen receptor, belonging to the family of chemokine receptors, has been shown to facilitate invasion by the malaria parasite, plasmodium vivax (Chaudhuri et al., 1993). Viruses such as HHV-6 an 7 and Epstein-Barr virus (EBV) are known to induce expression of CCR7, earlier defined as the EBIl receptor (Yoshida et al., 1997 Campbell et al.,... 

The US28-encoded chemokine receptor can serve as a coreceptor for human immunodeficiency virus (HIV) entry and play a role in cell-to-cell fusion between cells expressing HIV envelopes and those expressing pUS28 (Choe et al. 1998 Ohagen... 

Hill, C. M., Deng, H., Unutmaz, D., Kewalramani, V. N., Bastiani, L., Gorny, M. K., Zolla-Pazner, S., and Littman, D. R. (1997) Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simian immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor. J. Virol. 71, 6296-6304. 

Speck RF, Wehrly K, Platt EJ, et al. Selective employment of chemokine receptors as human immunodeficiency virus t)fpe 1 coreceptors determined by individual amino acids within the envelope V3 loop. / Virol. 1997 71(9) 7136-7139. 

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