Pharmacology human behavioral

Bickel, W.K., Hughes, J.R., and Higgins, S.T., Human behavioral pharmacology of benzodiazepines effects on repeated acquisition and performance of response chains, Drug Dev. Res., 20, 53, 1990. 

Animal Models and Human Drug Use Human Behavioral Pharmacology Ethical Issues Placebo Controls New Drug Development... 

BEHAVIORAL PHARMACOLOGY OF HUMAN DRUG DEPENDENCE. Travis Thompson, Ph.D., and Chris E. Johanson, Ph.D., eds. 

This section is a selective review of behavioral pharmacology studies in animals and humans that are consistent with a postsynaptic serotonergic action of LSD-like hallucinogens. (See also the chapters by Davis et al., Appel and Rosecrans, and Nichols and Glennon, this volume.)... 

Blanchard DC, Griebel G, Blanchard RJ (2001a) Mouse defensive behavior pharmacological and behavioral assays for anxiety and panic. Neurosci Biobehav Rev 25 205-218 Blanchard DC, Hynd AL, Minke KA, Minemoto T, Blanchard RJ (2001b) Human defense behaviors to threat scenarios show parallels to fear- and anxiety-related defense patterns of non-human mammals. Neurosci Biobehav Rev 25 761-770 Blanchard DC, Griebel G, Blanchard RJ (2003) The mouse defense test battery pharmacological and behavioral assays for anxiety and panic. Eur J Pharmacol 463 97-116 Blanchard RJ, Blanchard DC (1989) Anti-predator defense behaviors in a visible burrow system. J Comp Psychol 103 70-82... 

Vural Ozdemir Biomarker and Clinical Pharmacology Unit, VA Long Beach Healthcare System, Southern California Institute for Research and Education and Department of Psychiatry and Human Behavior, College of Medicine, University of California, Irvine, California, U.S.A. 

The drug self-administration procedure is perhaps the most obvious method in behavioral pharmacology through which research with animals can provide important information about human drug abuse. There are other important methods, however, and we now consider tw o of them drug discrimination and the conflict paradigm. 

Knowledge of the principles and methods of behavioral pharmacolog) in animals is essential to your understanding of new drug development. Before we get to that, however, we address questions about generalizing from animal research and using human subjects in drug research. 

Rush, C. R., Roll, J. M., 8c Higgins, S.T.( 1998). Controlled laboratory studies on the effects of cocaine in combination with other commonly abused drugs in humans. In S. T. Higgins 8c J. L. Katz (Eds.), Cocaine abuse Behavior, pharmacology, and clinical applications 239-264). San Diego Academic Press. 

Troisi, J. R., II, Critchfield, T. S., Griffiths, R. R. (1993). Buspirone and lorazapam abuse liabilit in humans Behavioral effects, subjective effects, and choice. Behavioural Pharmacology, 4, 217-230. 

Behavioral pharmacology The study of how medication interacts with human behavior... 

Mewaldt, S. P., Ghoneim, M. M. (1979). The effects and interactions of scopolamine, physostigmine and methamphetamine on human memory. Pharmacology Biochemistry and Behavior, 10, 205-210. 

Fischman M. W. and Johanson C. E. (1998) Ethical and practical issues involved in behavioral pharmacology research that administers drugs of abuse to human volunteers. Behav. Pharmacol. 9,479 98. 

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