Hughes. Edward

Huckel s rule, 423-429,432-433, 436 Huffman, Donald, 410 Hughes, Edward D., 306,315, 336 Hund s rule, 10... 

The mechanisms by which nucleophilic substitution takes place have been the subject of much study Extensive research by Sir Christopher Ingold and Edward D Hughes and their associates at University College London during the 1930s emphasized kinetic and stereochemical measurements to probe the mechanisms of these reactions... 

In a classic expenment Edward Hughes (a colleague of Ingold s at University College Lon don) studied the rate of racemization of 2 lodooctane by sodium iodide in acetone and compared It with the rate of incorporation of radioactive iodine into 2 lodooctane... 

Hughes, Jonathan. Arthurian myths and alchemy the kingship of Edward IV. Stroud (Glos) Sutton, 2002. xiii, 354 p. ISBN 0-7509-1994-9... 

Hughes, Jonathan. Edward IV and the alchemists Jonathan Hughes looks at the significance, in alchemical terms, of this reign, and what the king himself made of alchemical prophecy. Hist Today 52, no. 8 (1 Aug 2002) 10-17. 

Clive A. Edwards. The Impact of Pesticides on the Environment. In The Pesticide Question, 13-47. David Pimentel and Hugh Lehman, eds. New York Chapman and Hall, 1993. G. Fischer. Presentation Speech to Paul Mueller. Nobel Lectures, Physiology or Medicine, 1942-1962. New York Elsevier, 1964. Source for God-given substance English journal article and Swedish houseflies. 

Kelly JD, Archer CM, Platts EA, Storey AE, Canning LR, Edwards B, King AC, Burke JF, Duncanson P, Griffiths DV, Hughes JM, Pitman MA (1994) J Nucl Biol Med 38 472 (abstr)... 

Proposed by Edward D. Hughes and Sir Christopher Ingold (the University College, London) in 1937. 

Hughes, V., Humphreys, J. M., Edwards, S. W. (1987). Protein synthesis is activated in primed neutrophils a possible role in inflammation. Biosci. Rep. 7, 881-9. 

Edwards, S. W., Hughes, V., Barlow, J., Bucknall, R. (1988). Immunological detection of myeloperoxidase in synovial fluids from patients with rheumatoid arthritis. Biochem. J. 250, 81-5. 

The years 1939 to 1944 were spent at University College, Aberystwyth, where the chemistry department was evacuated from London. Then, as in the past few years, much of Ingold s work was carried out in collaboration with his postdoctoral research student and later colleague Edward D. Hughes. 12 One of their students, Otto Theodor Benfey, recalls that Ingold and Hughes often came round the laboratory at Aberystwyth each day asking what was new and... 

Edward David Hughes, 19061963." Biographical Memoirs of Fellows of the Royal Society 10 (1964) 147182. 

Both urinary and fecal excretion of 14C was determined in rats administered an oral dose of 1.2 mg/kg of [14C]-labeled phenol (Edwards et al. 1986). Rats excreted 80.3 11.2% in the urine and 1.8 1.6%inthe feces in 24 hours. In rats exposed orally to radiolabeled phenol, elimination was 95% complete after 72 hours, with the primary elimination route being through the urine (Hughes and Hall 1995). Fecal elimination was slower and less overall. 

Absorption of phenol occurs fairly rapidly via the inhalation (Hughes and Hall 1995 Ohtsuji and Ikeda 1972 Piotrowski 1971), oral (Capel et al. 1972 Edwards et al. 1986 French et al. 1974 Hughes and Hall 1995 Kao et al. 1979 Kenyon et al. 1995), and dermal (Baranowska-Dutkiewicz 1981 Hughes and Hall 1995 Piotrowski 1971) routes. Because it is an irritant, tissue damage, inflammation, or other irritation effects may occur at the sites of absorption. Because of its high pKa, ionization will not occur within the acid environment of the gut. The action of gut microflora on phenol breakdown is not expected to be significant. 

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