HPLC in Automated and Robot-Assisted Dissolution Testing

HPLC IN AUTOMATED AND ROBOT-ASSISTED DISSOLUTION TESTING [Pg.390]

Dissolution is one of the most time-consuming tests in stability testing, clinical release, and process support of pharmaceutical dosage [Pg.390]

Fully automated workstations can automatically fill vessels with dissolution medium, drop the tablets or capsules, collect multiple samples, and clean vessels. Zymark MultiDose Automated Dissolution Workstation (Zymark Corporation, Hopkinton, MA), Sotax AT70 Smart (Sotax Corporation, Horsham, PA), and AUTO DISS systems (Pharma Test GmbH, Hainburg, Germany) are several popular automated systems used within the pharmaceutical industry. [Pg.391]

The autosampling device is critical to the integrity of automated dissolution testing systems as it serves as the interface between the dissolution apparatus and the sample analysis systems. The autosampler takes [Pg.391]

3 The diagram of a typical automated dissolution system with on-line [Pg.391]

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