Host organism

A virus is a species containing DNA and RNA that can reproduce itself, but to do this, it needs to hijack the metabolism (cells) of a host organism, since it has no information itself with which to build cells. 

Drugs. Ttifluoromethyl-based pharmaceuticals had been limited to phenothiatine tranquilizers and benzothiadiazine 1,1-dioxide diuretics (qv). However, new dmgs have been developed (Table 11). One of the key properties of the CF group is its high lipophilicity it increases the Hpid solubiUty of the pharmaceutical and thus accelerates absorption and transport within the host organism. 

Parisitism One organism living on or in another to obtain nourishment, without provviding any benefit to the host organism.. 

Note that the following information will need to be modified to meet the needs of the eurrent organization. The size of the host organization and the roles of management within the organization are key items that need to be eonsidered. This information, as presented, is meant to elosely meet the needs of a mid-sized eompany. But no matter what size eompany will use this information, it will need modifieations. These modifieations will inelude forms and attaehments that have not been ineluded. We believe that eaeh host organization should develop its own proeedures, ineluding its own forms and attaehments to fit its needs, personnel, and business strueture. 

No matter how large or small an organization is, there will invariably be many times when a host organization will need to get outside assistanee to ensure that eertain work tasks will be properly eompleted. 

The process of engaging the required capabilities must be a formal process so that both the organization in need and the contractor/sub-contractor are protected in the event of a failure to perform, an accident, or a difference of opinion as to terms or performance. Adherence to the provisions of this procedure will help attain good contracting practices and minimize the potential liabilities to the host organization in contractual relationships. 

Host organization All companies, subsidiaries, affiliates, divisions, groups, joint ventures, or projects of host organization... 

Vendor An outside supplier of raw materials, supplies, equipment and minor services needed for the host organization to perform its operations (i.e.. Office Max provides office supplies). 

Establish the criteria for training the contractor/subcontractor. Review the completed contractor/subcontractor prequalification forms and provide an evaluation of the contractor/subcontractor s ability to meet the host organization s health and safety policies and procedures. Contractors/subcontractors must demonstrate their ability to meet established criteria, to the satisfaction of the health and safety professional, in order to be considered for prequalification. 

Have the ability and willingness to perform work in compliance with host organization policies and procedures, where those procedures go beyond regulatory requirements. 

This plan must identify (as a specific individual) all competent or qualified persons required by applicable regulations or host organization procedures. 

In the event of an emergency situation, and a contractor/subcontractor is required in an exchision/contaminated zone, an insurance certificate naming the host organization as the holder and meeting the... 

This form doeuments information related to eontraetors/subeontraetors with partieular emphasis on a reeord of good safety performanee and quality whieh meets your requirements so that the host organization may be provided with safety performanee and eost eontrol. Failure to eomplete and return this form will preelude qualifying a eontraetoiV subeontraetor to do work for the host organization. 

A copy of the general safety rules accompanied by a receipt form shall be included with the prequalification letter to a prospective contrac-tor/subcontractor. This document sets forth in broad terms the safety requirements with which a contractor/subcontractor is expected to conform while working under contract for the host organization. 

The purehase order is the means by whieh the host organization engages a qualified eontraetor/subeontraetor to perform speeifie serviees for the host organization. It must eontain the following terms in addition to those in the work agreement ... 

Equipment and faeilities to be provided by the host organization (if none, so state)... 

Only personnel who have completed the training prescribed by host organization health and safety personnel shall be allowed to work on host organization projects. Some projects may require contractor certification or special training as specified in the implementing purchase order. 

Health and Safety Compliance with Regulatory and Host Organization Requirements... 

Contractors are required to comply with all applicable federal, state, and local regulatory requirements, in addition to host organization requirements as described in company policies and procedures and the site-specific health and safety plan (H S plan). 

All lower tier subcontractors engaged by a contractor/subcontractor providing services to the host organization will be qualified in accordance with this procedure, the same as the contractor/subcontractor, with particular emphasis on the prequalification form, insurance requirements, and safety rules. A qualified contractor/subcontractor file shall be maintained by purchasing for each lower tier subcontractor employed by a contractor/subcontractor. 

Records of training conducted by host organization or others... 

All reports delivered to a client, or in the case of in-house projects on host organization premises, the reports presented to host organization management, must be a part of the project file. 

NOTE Contractors unable to meet host organization requirements for accident rates or experience modification rates may submit a written safety enhancement program designed to bring project performance in line with host organization requirements which will be implemented for all work done for the host organization. If approved by the host organization health and safety professional, the safety enhancement plan will become part of the contractor s job-specific safety plan and the contractor may be approved. 

Interferon (IFN) differs from bona fide antiviral diugs since it is a natural defense protein of the host organism and does not directly interfere with the viral replication steps. Interferons are small glycoproteins inducing immune modulatory and antiviral activities. They are secreted by lymphocytes, leukocytes and fibroblasts in response to foreign nucleic acids (dsRNA). 

Biotin can be synthesized by the human colon flora. The question to which extent this production contributes to covering the host-organism s requirements is, however, subject to discussion. In most foods of animal origin as well as in cereals, biotin prevails in the protein (= enzyme)-bound form as e-N-biotinyl-L-lysine (= biocytin). Brewer s yeast, liver, soya beans, and peanuts number among the biotin rich foods [1]. 

---