Hormonal status

Hepatic VLDL Secretion Is Related to Dietary Hormonal Status... 

Pelvic floor disease prior gynecologic surgery, hormonal status (pre- vs. postmenopausal) Constipation, diarrhea, fecal incontinence,... 

The choice of therapy for metastatic disease is based on the site of disease involvement and presence or absence of certain characteristics (i.e., hormonal status of the primary tumor and disease location). For example, patients who experience a long DFS following local-regional therapy or have disease that is located primarily in the bone or soft tissue likely will respond to endocrine therapy. Patients with asymptomatic visceral involvement (e.g., liver or lung) may be candidates for hormonal therapy depending on the clinical circumstance (generally... 

Reproductive Effects. There is sufficient qualitative evidence to support the conclusion that at high occupational exposure levels lead has significant adverse effects on human reproduction, including increased incidences of spontaneous abortion, miscarriages, and stillbirths. The mechanisms responsible for these effects are unknown at this time, but many factors may contribute to these results. These factors include indirect effects of lead on maternal nutrition or hormonal status before and during pregnancy to... 

Patient age and hormonal status in women should be considered in the initial evaluation of patients with skin disorders. Older patients are predisposed to developing psoriasis, seborrhea, and other skin conditions. Atopic dermatitis is most likely to occur in children. Menopausal women tend to develop brown hyperpigmentation, or melasma. Pregnant women may develop hyperpigmentation of the areola and genitalia as well as melasma. 

Voipio SK, Komi J, Kangas L, Halonen K, DeGregorio MW, Erkkola RU (2002) Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women. Maturitas 43(3) 207-214... 

Bioavailability of Ca2+ is affected by numerous physiological conditions, including age, sex, genetic make-up, stress, hormonal status, health status, and nutritional habits. In addition to these intrinsic factors, certain dietary components, such as fiber and oxalate, form insoluble complexes with Ca2+ and interfere with its absorption. Another putative culprit in this category is phytic acid. 

Age, calcium intake, hormonal status, exercise and vitamin status have all been implicated in the development of osteoporosis. Estrogen levels represent an important factor in skeletal calcium retention and homeostasis. In therapeutic trials in which post-menopausal women were given daily doses of estrogens, such therapy has been demonstrated to be partially effective in reducing the rate of bone resorption. However, this therapy has the concomitant hazard of endometrial cancer (10). Vitamin D and its hormones have been given considerable attention in the more recent studies. Without adequate dietary and tissue levels of such vitamins, calcium absorption and bone status will be impaired. 

Mulay, S., Varma, D.R. and Solomon, S. (1982). Influence of protein deficiency in rats on hormonal status and cytoplasmic glucocorticoid receptors in maternal and fetal tissues. J. Endocrinol. 95 49-58. 

Roy, S., Vega-Lopez, S., and Eemandez, M. L. (2000). Gender and hormonal status affect the hjrpolipidemic mechanisms of dietary soluble fiber in guinea pigs. /. Nutr. 130, 600-607. 

Metabolic clearance of caffeine is altered according to menstrual phase and hormonal status in women (Lane et al. 1992). Clearance is slower during the late luteal phase compared to the follicular phase, prior to the onset of menstruation. However, the size of the effect and significance in everyday activity remains in question. 

Culliford D, Hewitt HB. 1957. The influenee of sex hormone status on the suseeptibility of miee to ehloroform-induced necrosis of the renal tubules. J Endoerinol 14 381-393. 

Smith JH, Malta K, Sleight SD, et al. 1984. Effect of sex hormone status on chloroform nephrotoxicity and renal mixed function oxidases in mice. Toxicology 30 305-316. 

Ilcol, Y. O., Hizli, Z. B., and Ozkan, T. (2006). Leptin concentration in breast milk and its relationship to duration of lactation and hormonal status. Int. Breastfeed ]. 1, 21. 

The question of maternal toxicity has been referred to as vexed. This is because of the difficulty in deciding what, exactly, maternal toxicity is and how it might influence the conceptus. There seems to be an assumption on the part of some applicants that if maternal toxicity occurs, then there is no need to consider the effects or interrogate the data any further. While there are data to show that in some species, stress can influence the hormonal status of the animals and that under these conditions malformations can be induced (11), it is not clear that this will occur in all cases. In the author s experience, it is possible to have adult animals in poor condition that go on to deliver healthy and anatomically normal offspring. 

The Sertoli cells in the testes appear to be the main target of the testicular toxicity. Proposed mechanistic h otheses relate to reduced testicular zinc levels, altered hormonal status, altered metabolic function and altered follicle-stimulating hormone reactivity. 

Mateo L, Nolla JM, Bonnin MR, Navarro MA, Roig-Escofet D. Sex hormone status and bone mineral density in men with rheumatoid arthritis. J Rheumatol 1995 22(8) 1455-60. 

Since hormone status could be involved in the occurrence of irritable bowel syndrome, the risk has been examined in women using hormone replacement therapy (56). 

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