Hemoglobin anemia

Anemia characterized by an inadequate amount of iron in the body to produce hemoglobin Anemia resulting from a reduced production of erythropoietin, a hormone secreted by the kidney that stimulates the produdion of red blood cells (RBCS)... 

Iron Liver, lean meat, whole grains, dark green vegetables Component of enzymes tuid hemoglobin Anemia... 

The most commonly reported adverse reactions reported (>35% of subjects) in clinical trials of patients receiving boceprevir (as part of the triple therapy with PR) were fatigue, anemia, nausea, headache, and dysgeusia. The addition of boceprevir to PR therapy is associated with an additional decrease in hemoglobin (anemia) compared with PR alone and may also result in worsening of neuhopenia. ... 

Sickle-cell anemia is the classic example of an inherited disease that is caused by a change in a protein s amino acid sequence. Linus Pauling proposed in 1949 that it was caused by a defect in the hemoglobin molecule he thus coined the term molecular disease. Seven years later Vernon Ingram showed that the disease was caused by a single mutation, a change in residue 6 of the P chain of hemoglobin from Glu to Val. 

Anemia is a decrease in the number of red blood cells (RBCs), a decrease in die amount of hemoglobin in RBCs, or bodi a decrease in die number of RBCs and hemoglobin. When diere is an insufficient amount of hemoglobin to deliver oxygen to die tissues, anemia exists. There are various types and causes of anemia For example, anemia can be die result of blood loss, excessive destruction of RBCs, inadequate production of RBCs, and deficits in various nutrients, such as in iron deficiency anemia Once the type and cause have been identified, die primary health care provider selects a method of treatment. 

Iron deficiency anemia is by far die most common type of anemia Iron is a component of hemoglobin, which is in RBCs. It is the iron in the hemoglobin of RBCs diat... 

Iron salts, such as ferrous sulfate or ferrous gluconate, are used in the treatment of iron deficiency anemia, which occurs when there is a loss of iron that is greater than the available iron stored in the body. Iron preparations act by elevating the serum iron concentration, which replenishes hemoglobin and depleted iron stores. 

Iron deficiency Anemia characterized by an inadequate amount of iron in the body to produce hemoglobin... 

InFeD, generic anemia soreness and inflammation at injection site, chest pain, arthralgia, backache, convulsions, pruritus, abdominal pain, nausea, vomiting, dyspnea weight and grams percent (g/dL) of hemoglobin IV, IM... 

A healthy adult human body contains about 3 g of iron, mostly as hemoglobin. Because about 1 mg is lost daily (in sweat, feces, and hair), and women lose about 20 mg in each menstrual cycle, iron must be ingested daily to maintain the balance. Iron deficiency, or anemia, results in reduced transport of oxygen to the brain and muscles, and an early symptom is chronic tiredness. 

Anemias, reductions in the number of red blood cells or of hemoglobin in the blood, can reflect impaired synthesis of hemoglobin (eg, in iron deficiency Chapter 51) or impaired production of erythrocytes (eg, in folic acid or vitamin Bjj deficiency Chapter 45). Diagnosis of anemias begins with spectroscopic measurement of blood hemoglobin levels. 

Mlcrochromatographlc Methods During the past two years rapid. Inexpensive, miniaturized column chromatographic methods for the separation of hemoglobins have been developed These methods are designed for the qualitative detection and quantitative determination of hemoglobins In normal and abnormal conditions and cover the quantitation of Hb-A2 the detection of Hb-S, Hb-C other abnormal Hbs differentiation of various conditions In adults and the detection of hemoglobinopathies especially sickle cell anemia at birth (27, 28, 29, 30) ... 

Unstable hemoglobin variants are often found In persons with unexplained hemolytic anemias. Below are some guidelines for their detection. 

An Attempt to Unify Some Observations In Thalassemia and In Related Conditions". Proc. Third Cooley s Anemia Conf. April, 1973. Ann. N. Y. Acad. Scl., (1974), 232 107. Hulsman, T. H. J. "Normal and Abnormal Hemoglobins". 

Additionally, with chronic hypoxia, normal hemoglobin and hematocrit values may represent relative anemia.12 Increased red blood cell production is a physiologic response to hypoxia however, this response may be blunted in CF and may result in symptoms of anemia despite normal lab values. Abnormal bleeding may also be observed as a result of vitamin K malabsorption or antibiotic-associated depletion of gastrointestinal flora and vitamin K synthesis. 

Anemia (decreased hemoglobin and hematocrit) occurs as a result of variceal bleeding, decreased erythrocyte production, and hypersplenism. 

Ribavirin causes a dose-related hemolytic anemia. Once treatment has been initiated, the hemoglobin concentration may... 

---