Heat-stress-induced protein

Brassica oleraceae (cabbage) (Brassicaceae) Water-soluble chlorophyllcarrying protein (WSCPI) heat-stress-induced protein (HTI) (24 kDa) Serine protease [339- 341]... 

Heat stress is an environmental factor responsible for oxidative stress. We reported that reactive oxygen species (ROS) production by mitochondria was significantly increased in skeletal muscle of birds after exposure to heat stress (Mujahid et al., 2007), and that muscle mitochondria from heat-stressed birds also had the higher mitochondrial membrane potential (AT) (M. Kikusato, unpublished data). These results implied that the overproduction of ROS may depend on AT. We also found that heat stress significantly decreased avian uncoupling protein (avUCP) in muscle mitochondria (Mujahid et al., 2009). Therefore, this decrease may contribute to excess ROS production, possibly via a depression of inducible proton leak. To elucidate more precisely the mechanism involved in the overproduction of mitochondrial ROS under heat stress conditions, we have attempted to clarify how heat stress-induced ROS production depends on AT, and to evaluate the effect of avUCP downregulation on the inducible proton leak. 

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Exposure of cells to elevated temperatures, or heat shock, induces the transcription and translation of a set of proteins known as the heat-shock proteins (HSPs) or the stress proteins. This event usually occurs with the concomitant inhibition of biosynthesis of other cellular components. The response is believed to be an attempt by the cells to protect themselves from injury, and there is some evidence to indicate that it may also be linked to oxidative stress. Evidence in favour of this idea comes from observations such as the following ... 

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