Hank’s solution

Assis SL, Rogero SO, Antunes RA, Padilha AF, Costa I. A comparative study of the in vitro corrosion behavior and cytotoxicity of a superferritic stainless steel, aTi-13Nb-13Zr alloy, and an austenitic stainless steel in Hank s solution. Journal of Biomedical Materials Research B 2005, 73, 109-116. 

Zhou, X. and Mohanty, P. (2012a) Electrochemical behaviour of cold sprayed hydroxyapatite/titanium composite in Hank s solution. Electrochim. Acta, 65, 134-140. 

Metikos-Hukovic, M., Pilic, Z., Babie, R., Omanovic, D. Influence of alloying elements on the corrosion stability of CoCrMo implant alloy in Hank s solution. Acta Biomater. 2, 693-700 (2006)... 

Table la.29 Rate of formation of corrosion products for the stainless steel X2CrNiMol7133 in Hank s solution during current-time-tests (Ref. 24)... 

Table la.32 Repassivation time of the stainless steel X2CrNiMol7133 in 0.9% NaCl and breakdown potential in Hank s solution (Ref. 21)... 

Figure 9.11 Anodic polarization curves for MA956 in the as-received and oxidized conditions after nine months of immersion in Hank s solution. O Oxidized as-received. (Escudero and Gonzalez-Carrasco, 1994.)...

In these studies, the diaphragm muscle tissue used was obtained from mice. The isolated tissue was equilibrated to Hank s solution, a defined nutrient media, for a minimum of 6 hours at 4 C. It was found that this tissue retained its viability for at least 24 hours stored in this fashion. 

Witte et al. [79] found that the corrosion rates of AZ91D and LAE442 measured in vivo were orders of magnitude lower than those measured in substitute ocean water prepared according to ASTM-Dl 141-98 [80]. Subsequently, in vitro testing has been carried out in a variety of solutions including (i) Hank s solution, (ii) simulated body fluid (SBF), (iii) artificial plasma (AP), (iv) phosphate buffered saline (PBS) and (v) minimum essential medium (MEM, Invitrogen). 

Figure 3.29 shows hydrogen evolution data for a range of Mg alloys in Hanks s solution at 37 °C [81]. In agreement with the trends discussed above. 

Average corrosion rate for Mg-1.0Mn-1.0Zn in Hank s solution and SBP as a function of immersion time. Reprinted with permission from Yang and Zhang [84]. 

The surface film has been found to contain magnesium carbonate and hydroxyapatite (magnesium apatite) and it has been suggested [84,91,92] that these form by the interaction of Mg ions with the calcium, carbonate and phosphate ions which are constituents of Hank s solution and SBF, by the following precipitation reactions ... 

Corrosion behavior of uncoated and Ti02 deposited Ti6A14V was evaluated by Karpagavalli et al. (2007) in freely aerated Hank s solution at 37°C by the measurement and analysis of open circuit potential variation with time, Tafel plots and electrochemical impedance spectroscopy. The electrochemical results indicated that nano Ti02 coated Ti6A14V showed a better corrosion resistance (Table 5.7, Fig. 5.14) in simulated biofluid than uncoated Ti6A14V. 

Table 5.7 and 1 and corrosion rate determined from theTafel plots of uncoatedTi6AI4V andTiOj depositedTi6AI4V in Hank s solution at 37°C... 

Tafel plots ofTiOj depositedTI6AI4V and uncoatedTi6AI4V in Hank s solution at37°C (Karpagavalli etal., 2007)... 

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