Haarmann Reimer

Pfi2er, Monsanto Sterling, Takeda Haarmann Reimer, Takeda EMC, Monsanto, RhcJ)ne-Poulenc... 

Universal Foods (Wamer-Jenkinson, McCormick/Stange, Kohnstamn), Haarmann Reimer, Hoffmann-La Roche, Colorcon, Quest/Biocon... 

International Flavors and Fragrances, Quest International, Givaudan, Takasago, Haarmann Reimer... 

H. Fiege and co-workers. Proceedings 2nd International Haarmann-Reimer Symposium, 1980, pp. 63—75. 

P. W. Staal, Chelation, Technical Bulletin A-1014, Haarmann Reimer Corp., Springfield, N.J., 1989. 

Haarmann Reimer Corp. data 1990 Citric Acid, Chemical Economics Handbook, Stanford Research Institute, Menlo Park, Calif., May 1989. 

In 1874, Holzminden chemists Ferdinand Tiemann and Wilhelm Haarmann first succeeded in synthesising vanillin from coniferin. Holzminden became the site where vanillin was first produced industrially. Haarmann Reimer was the world s first factory in which synthetic scents and flavourings were produced [5]. 

Williams PJ, Sefton MA, Marinos VA (1993) 3rd international Haarmann Reimer symposium on recent developments in flavor and fragrance chemistry, Tokyo, p 283 Winterhalter P, Skouroumounis GK (1997) Adv. Biochem. Eng. 55 73 Fischer U, Trautmann S, Binder G, Wilke A, Goritz S (2000) Intensivierimg des Weinaromas. KTBL, Darmstadt, p 121... 

Haarmann Reimer (Holzminden, Germany) in collaboration with Rolf Schmid s group at the University of Stuttgart developed a process based on the resolution of racemic menthol esters, such as acetate or benzoate esters. The team employed several lipases such as Candida cyclindracea which resulted in enantio-selectivities up to 100% e.e. (Bomscheuer, 2002). 

While the advertisements of Haarmann Reimer, Springfield, New Jersey, emphasize the natural approach, a spokeman agreed that they use Maillard technology, especially in the production of meat flavors. 

Once mycelia have been separated via continuous filtration from exhausted production media, citric acid may be recovered by using three different methods, such as direct crystallization upon concentration of the filtered liquor, precipitation as calcium citrate tetrahydrate, or liquid extraction. Since molasses are extremely rich in impurities, direct crystallization cannot be applied unless very refined raw materials, such as sucrose syrups or crystals, are used. The precipitation process (that is based on subsequent addition of sulfuric acid and lime to clarified fermentation broths) is used by the great majority of world citric acid manufacturers, including Archer Daniels Midland Co. (ADM) in the United States. Liquid extraction with mixtures of trilaurylamine, n-octanol, and Cio or Cn isoparaffin was used by Pfizer Inc. in Europe and Bayer Co. (formerly Haarmann Reimer Co., subsidiary of Miles) in the Dayton (OH, USA) and Eikhart (IN, USA) plants only (Moresi and Parente, 1999), even if such plants might have been shut down in 1998. 

Hopp R (1993) Some highlights of H8tR research a review of nearly 120 years of research at Haarmann Reimer. In Hopp R, Mori K (eds) Recent developments in flavour and fragrance chemistry. VCH Publishers, Weinheim, Germany, p 14... 

Likewise, vanillin is now largely produced synthetically. The world leader in this area is Rhone-Poulenc, which has a unit in Saint-Fons to which was added a unit bought from Monsanto in 1986 on the West Coast of the United States. In the latter plant, vanillin is still extracted from paper pulp liquor. Menthol from plantations in Brazil and China is also produced by synthesis since Haarmann Reimer, bought by Bayer in 1954, managed to carry out industrially the resolution of racemic menthol, thus isolating the levoiso-mer. Anethole, synthesized by Hercules from pine oil, is two to three times cheaper than when it is extracted from star anise. 

While Bayer s association with Haarmann Reimer proved successful, it took Hercules several years, from 1973 on, to understand properly how its Polak Frutal Works (PFW)... 

Among the contrarians, Bayer has had for historical reasons a different approach to the problem of remaining a well-rounded producer of chemicals. It has always been a leader in such specialty chemicals as plastics and rubber additives and supplies master batches through its subsidiary Rhein Chemie. Its polymers are mainly centered on synthetic elastomers and specialty plastics like polyurethanes and polycarbonates that Bayer itself develops. These are not subjected to the cutthroat competition that commodity thermoplastics are. Bayer has remained involved in aroma chemicals with a well-known subsidiary, Haarmann Reimer. In pharmaceuticals the company occupies an honorable rank, although in the future its management may want to separate that branch from the rest of its activities in preparation for further alliances. Like BASF, Bayer considers its agrochemical line as a core business. However, unlike BASF, it is less interested in integrating upstream production to oil raw... 

Haarmann Reimer, Fragrance Guide Duftattas, Atlas Olfactif Gloss Verlag Hamburg, 1997. 

Assignee Haarmann Reimer GmbH Utility Fragrances and Perfumes... 

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