Gypsophila species

Saponins Produced by Gypsophila Species Enhance the Toxicity of Type I Ribosome-Inactivating Proteins... 

As it can be clearly seen Fig. 2 that Gypsophila species (Caryophyllaceae) are an especially rich source of triterpenoidal saponins [18-20]. Gypsophila saponins are of interest in terms of their applications in vaccines [21]. Saponi-num album (Merck) is a complex mixture of triterpenoid saponins from Gypsophila paniculata and Gypsophila anostii which used to be commercially... 

Cell suspension cultures of Gypsophila paniculata and Saponaria officinalis produce very closely related triterpenoid saponins. Pretreatment of cell suspension cultures of G. paniculata with gypsogenin 3,0-glucuxonide (a triterpenoid saponin precursor in G. paniculata) followed by administration of [ C] acetate resulted in a marked reduction in incorporation of radioactivity into saponins and their precursors, but not into sterols and steryl glycosides [26]. Measurements of OSC activities revealed that there was no effect of elicitor treatment on CS levels in either species, but in G. paniculata AS levels went down while in S. officinalis they increased. This suggests that in these two species OSCs are regulating steps in the isoprenoid pathway and control the flux to sterols and triter-penes. 

Saponariae albae radix White soapwood root Gypsophila paniculate L., and other G. species Caryophyllaceae MD... 

Adjuvant activity has also been observed with saponins from Gypsophila and Saponaria (Caryophyllaceae) whereas it was absent with other saponin containing extracts prepared from Soya Alfalfa Chenopodium quinoa and Glycyrrhiza radix [15]. Since the strongest adjuvant activity was observed with saponins from Quillaja saponaria we will describe the activities associated with saponins from this species. 

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