Growth impairment

Steiner TS, Lima AAM, Nataro JP, Guerrant RL Enteroaggregative Escherichia coli produce intestinal inflammation and growth impairment and cause interleukin-8 release from intestinal epithelial cells. J Infect Dis 1998 177 88-96. 

Table 15. (BBodSchV - Annex 2,2.4, p. 53) Soil - Plant Pathway Agriculture with regard to growth impairments of cultivated plants Trigger Values.

Agriculture with regard to growth impairments of cultivated plants ... 

Essential to ascidians ("sea squirts"), which concentrate in a miilionfold from sea water. Essential to chicks and rats. Deficiencies cause reduced growth, impaired reproduction and sirvival of young, impaired tooth and bone metabolism and feather development.4 May be a factor in manic-depressive illness/ Essential involved in gkicose metabolism and diabetes potentiates effect of insulin. Presence in glucose tolerance factor from brewer s yeast questioned/... 

Lai HC, FitzSimmons SC, Allen DB, Kosorok MR, Rosenstein BJ, Campbell PW, Farrell PM. Risk of persistent growth impairment after alternate-day prednisone treatment in children with cystic fibrosis. N Engl J Med 2000 342(12) 851-9. 

Schultz, T.W., Seward-Nagel, J., Foster, K.A. and Tucker, V.A. (2004) Population growth impairment of aliphatic alcohols to Tetrahymena, Environmental Toxicology 19, 1-10. 

Schultz, T.W., Tetratox Tetrahymena pyriformis population growth impairment endpoint a surrogate for fish lethality, Toxicol. Methods, 7, 289-309, 1997. 

In this present analysis concerns about quality, transparency, and domain identification are addressed in the validation of a previous developed QSAR. This QSAR examines the prediction of ectotoxic potency for population growth impairment to the aquatic ciliate Tetrahymena pyriformis by substituted benzenes. 

Seward, J.R., Sinks, G.D., and Schultz, T.W., Reproducibility of toxicity across mode of toxic action in the Tetrahymena population growth impairment assay, Aquatic Toxicol., 53, 33 47, 2001. 

The cytokine subfamily 1 includes erythropoietin (EPO) (that increases red blood cell production and has accordingly been involved in sports drug abuse), granulocyte colony stimulating factor (G-GSF) (that stimulates leucocyte differentiation), GH (used clinically for growth impairment due to GH deficiency), prolactin (PRL) (that promotes milk production), IL-4 and IL-7. The members of this family act via homodimeric receptors. The leucocyte-derived cytokines of this group variously modulate haematopoiesis and immune responses. 

There was no evidence that fluoxetine or other SSRIs caused an increase in intrauterine death, significant birth defects, or growth impairment. Follow-up behavioral studies of infants exposed to SSRIs during pregnancy also showed no difference from controls. In a summary of systematic reviews of the safety of SSRIs in pregnancy and lactation the authors concluded that thus far there is little evidence that SSRIs cause birth defects... 

The issue of deferoxamine osteochondropathy is even more complex, because thalassemia itself is also associated with growth impairment and body disproportion-ality with truncal shortening, whether puberty is induced or spontaneous (101). 

Holtkamp K, Peters-Wallraf B, Wuller S, Pfaaffle R, Herpertz-Dahlmann B. Methylphenidate-related growth impairment. J Child Adolesc Psychopharmacol 2002 12(1) 55-61. 

In animals Mn deficiency causes poor growth, impairs the ability to stand from a supine position, and causes swelling and disorganization of the endoplasmic reticulum and defects in the mitochondrial membrane. Mn deficiency in mother rats produces offspring with a variety of skeletal abnormalities, such as leg bones that are disproportionately short in comparison with the rest of the body. The offepring also have tremors and ataxia. In humans, Mn deficiency results in a scaly, red rash on the skin of the upper torso. Plasma levels of calcium alkaline phosphatase increase, suggesting that Mn deficiency provokes the net dissolution of bone (bone resorption) (Freeland-Graves and Turnlund, 1996). 

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