Growth hormone adults

Alberts A., Jackintell L. and Phillips J. (1994). Effects of chemical and visual exposure to adults on growth, hormones, and behavior of juvenile Green Iguanas. Physiol Behav 55, 987-992. 

Identify the clinical features of children and adults with growth hormone deficiency and select appropriate pharmacotherapy for these patients. 

Recombinant growth hormone therapy is the main pharmacologic treatment for growth hormone deficiency in both children and adults. 

Growth Hormone Deficiency in Adults Patient Care and Monitoring... 

Gharib H, Cook DM, Saenger PH, et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for growth hormone use in adults and children—2003 update. Endocr Pract 2003 9(1) 64-76. 

Simpson H, Savine R, Sonksen P, et al. Growth hormone replacement therapy for adults into the new millennium. Growth Horm IGF Res 2002 12(l) l-33. 

Jorgensen, J. and Christiansen, J. (eds). 2005. Growth Hormone Deficiency in Adults. S. Karger AG. Juul, A. 2000. Growth Hormone in Adults. Cambridge University Press. 

E6. Eden, S., Wiklund, O., Oscarsson, J., Rosen, T., and Bengtsson, B. A., Growth hormone treatment of growth hormone deficient adults results in a marked increase in lipoprotein(a) and HDL-cholesterol concentration. Atheroscler. Thromb. 13, 296-301 (1993). 

Juul, A. (2000). Growth Hormone in Adults. Cambridge University Press, Cambridge. 

Molitch ME, Clemmons DR, Malozowski S, Merriam GR, Shalet SM, Vance ML et al. Evaluation and treatment of adult growth hormone deficiency an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2006 91 1621-34. 

Growth hormone, or somatotropin, is a protein that stimulates linear body growth in children and regulates cellular metabolism in both adults and children. Growth hormone stimulates lipolysis, enhances production of free fatty acids, elevates blood glucose, and promotes... 

Coplan, J.D., Smith, E.L., Trost, R.C., Scharf, B.A., Altemus, M., Bjornson, L., et al. (2000) Growth hormone response to clonidine in adversely reared young adult primates relationship to serial cerebrospinal fluid corticotropin-releasing factor concentrations. Psychiatry Res 95 93-102. 

Hollander, E., Novotny, S., Allen, A., Aronowitz, B., and DeCaria, C. (2000) The relationship between repetitive behaviors and growth hormone response to sumatriptan challenge in adult autistic disorders. Neuropsychopharmacology 22 163-167. 

Colle, M., Rosenzweig, R, Bianchetti, G., Fuseau, E., Ruffle, A., Rue-das, E., and Morselli, P.L. (1991) Nocturnal profile of growth hormone secretion during sleep induced by zolpidem a doubleblind study in young adults and children. Norm Res 35 30-34. 

GH synthesis and secretion does not disappear when linear growth is complete. In fact isolation of hGH from cadaver pituitary glands would not have been possible if it did. Physicians caring for adult patients with pituitary disease began to realize that even with optimum replacement of other hormones, patients who acquired GH deficiency in adulthood complained bitterly about diminished quality of life. Studies from Europe also documented increased cardiovascular morbidity and mortality in these patients [13], Because it was no longer necessary to conserve scarce supplies of hGH for use in children, physicians were able to study GH effects in adults with growth hormone deficiency. These studies have shown that GH improves body composition (decreases fat mass and increases lean body mass) and decreases risk factors for cardiovascular disease [14]. 

Hintz, R.L., R.G. Rosenfeld, D.M. Wilson, A. Bennett, J. Finno, B. McClellan, and R. Swift, Biosynthetic methionyl human growth hormones is biologically active in adult man. Lancet, 1982.1(8284) 1276-9. 

Bengtsson, B.A., G. Johannsson, S.M. Shalet, H. Simpson, and RH. Sonken, Treatment of growth hormone deficiency in adults. J Clin Endocrinol Metab, 2000. 85(3) 933 2. 

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