Green Chemistry Assistant

Hanson, R. Campbell, P. Christianson, A. Klingshim, M. Engler, R. Green Chemistry Assistant. http //fusion.stolafedu/gca (accessed Jan 10, 2008). 

Enzyme-mediated oxidation reactions offer highly diverse options for the modification of existing functional groups as well as for the introduction of novel function in chiral catalysis. Biooxidations often enable us to obtain complementary solutions to metal-assisted transformations and organocatalysis and are considered one of the important strategies of green chemistry . 

The multi-component systems developed quite recently have allowed the efficient metal-catalyzed stereoselective reactions with synthetic potential [75-77]. Multi-components including a catalyst, a co-reductant, and additives cooperate with each other to construct the catalytic systems for efficient reduction. It is essential that the active catalyst is effectively regenerated by redox interaction with the co-reductant. The selection of the co-reductant is important. The oxidized form of the co-reductant should not interfere with, but assist the reduction reaction or at least, be tolerant under the conditions. Additives, which are considered to contribute to the redox cycle directly, possibly facilitate the electron transfer and liberate the catalyst from the reaction adduct. Co-reductants like Al, Zn, and Mg are used in the catalytic reactions, but from the viewpoint of green chemistry, an electron source should be environmentally harmonious, such as H2. 

Nadagouda, M.N. and Varma., R.S. (2006) Green and controlled synthesis of gold and platinum nanomaterials using vitamin B2 density-assisted self-assembly of nanospheres, wires and rods. Green Chemistry. 8 516-518. 

Julie A. Haack is a senior instructor and assistant department head for chemistry at the University of Oregon, where her work has focused on the incorporation of green chemistry principles into the introductory chemistry curriculum for both science and nonscience majors. She is a leader in facilitating the identification, development, and dissemination of green chemistry educational materials throughout the chemistry curriculum. 

First and foremost, I would like to thank all of the students and teaching assistants of Chemistry 337 and 338 at the University of Oregon for teaching me most of what I know about green chemistry. I would also like to thank Drs. Ken Doxsee, Jim Hutchison, and Julie Haack for their help with learning green chemistry. Finally, I would like to thank Drs. Peter Wuts of Pfizer Pharmaceuticals and Dr. Doug E. Frantz of the University of Texas Southwestern Medical Center for their help with some of the industrial examples. 

Hoogenboom, R. and U.S. Schubert, Microwave-Assisted Cationic Ring-Opening Polymerization of a Soy-Based 2-Oxazoline Monomer, Green Chemistry, 8, 895-899 (2006). 

Niichter, M., B. Ondruschka, W. Bonrathand A. Gum, Microwave Assisted Synthesis - A Critical Technology Overview, Green Chemistry, 6, 128-141 (2004). 

Penieres-Carrillo, G., Garcia-Estrada, J.-G., Gutierrez-Ramirez, J.-L., and Alvarez-Toledano, 2003. Infrared-assisted eco-friendly selective synthesis of diindolylmethanes. Green Chemistry, 5 337-39. 

Fraga-Drubreuil, J. and Cherouvrier, J.R. 2000. Clean solvent-free dipolar cycloaddition reactions assisted by focused microwave irradiations for the synthesis of new ethyl 4-cyano-2-oxazoline-4-carboxylates. Green Chemistry, 2 226-29. 

Kumar, H.M.S., Subba Reddy, B.V., Reddy, E.J., and Yadav, J.S. 1999. Microwave-assisted eco-friendly synthesis of 2-alkylated hydroquinones in dry media. Green Chemistry, l-.Ul-Al. 

Ranu, B.C., Guchhait, S.K., Ghosh, K., and Patra, A. 2000. Construction of bicyclo-[2.2.2] octanone systems by microwave-assisted solid phase Michael addition followed by AI2O3-mediated intramolecular aldolisation. An eco-friendly approach. Green Chemistry, 1 5-6. 

Neochoritis CG, Zarganes-Tzitzikas T, Tsoleridis CA et al (2011) One-pot microwave assisted synthesis under green chemistry conditions, antioxidant screening, and cytotoxicity assessments of benzimidazole Schifif bases and pyrimido[l, 2-a]benzimidazol-3(4H)-ones. Eur 1 Med Chem 46 297-306... 

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