Golden ragwort

Comfrey (Symphytum officinale) Uses Topical treatment of wounds, bruises, sprains, inflammation Action Multiple chemical components, allantoin promotes cell division, rosmarinic acid has anti-inflammatory effects, tannin possesses astringent effects, mucilage is a demulcent w/ anti-inflammatory properties, pyrrolizidine alkaloids cause hepatotox Available forms Topical application w/ 5—20% of herb applied on intact skin for up to 10 d Contra Do not take orally d/t hepatotox, do not use if PRG or w/ lactation Notes/SE N/V, exfoliative dermatitis w/ topical use Interactions T Risk of hepatotox W/ ingestion of borage, golden ragwort, hemp, Petasites EMS None... 

Senecio. Golden ragwort squaw weed life root. Dried plant of Senecio aureus L., Compositae. Habit. Can -ada and Eastern U.S. Constit. The alkaloids, senecifoline,... 

Furanoeremophilan-9-one, a constituent of golden ragwort (squaw weed, life root) from the dried plant of Senecio aureus, (+)-furanoeremophilen-3-one from Senecio nemorensis, (-)-l,10-epoxyfuranoeremophilane from Senecio glastifolius, and (-)-l,10-epoxyfuranoeremophilan-6,9-dione from Senecio smithii represent typical examples. 

Senecio spp. including golden ragwort proves to be a source of fatal poison that affects cattle [32]. Furthermore, the toxic effects are usually not detected until irreversible liver damage has occurred [33]. S. latifolius leaves are equipped as to treat wounds and bums, whereas decoctions are used to induce abortion or to cure infants [1,5, 34—37]. 

Enlargement of the liver and distension of the abdominal cavity were evident in cattle after ingestion of golden ragwort [42-44]. 

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