Glycyrrhizin, aglycon

The saponin is glycyrrhizin and consists of the aglycone glycyrrhetinic acid and two molecnles of glucuronic acid. It is abont 50 times sweeter than sucrose, but the aglycone has no sweet taste. The content of glycyrrhizin is 8-12% in the drug and 20-25% in the extract. 

Saponins 8%-12% glycyrrhizin calcium salt of glycyrrhizic acid no hemolytic activity the aglycone gjycyrrhetic add is active. 

Fig. IA Liquiritiae radix (1) shows glycyrrhizin (Tl) as a queiidiing band, at R, 0.25-0.3, tliree quendiing zones of flavonoid glycoside,s and chalcone,s in the R, range 0.65-0.75 and the aglycones at the solvent front.

Glycyrrhizin is a glycoside with a uronic acid disaccharide, 2-0-P-D-glucopy-ranosyl uronic acid-a-D-glucopyranosyl uronic acid, attached to a polyterpenoid aglycone (see Fig. 5.6D). It is found in licorice root and is 50 times sweeter than sucrose, with a licorice taste [22]. Glycyrrhizin has medical and dental applications it has been used to treat ulcers it also has been used as an antiinflammatory... 

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