Glycine sucrose system

Shalaev, E.Yu., Kaney, A.N. Study of the solid-liquid state diagram of the water- glycine-sucrose system. Cryobiology 31, 374-382, 1994... 

By contrast. Figure 2a shows a hypothetical isothermal cut through a state diagram for a ternary aqueous mixture in which water and one solute (e.g. glycine) can crystallise under certain conditions, but the other solute (e.g. sucrose) will invariably vitrify.Results from a detailed investigation of the water-glycine-sucrose system, including... 

Suzuki, T. Franks, F. Solid-liquid phase transitions and amorphous states in ternary sucrose-glycine-water systems. J. Chem. Soc., Faraday Trans. 1993, 89, 3283-3288. 

Kassraian, K. Spitznagel, T. Juneau, J. Yim, K. Characterization of the sucrose/glycine/water system by differential scanning calorimetry and freeze drying microscopy. Pharm. Develop, and Technol. 1998, 3, 233-239. 

The use of a cooling accessory permits XRD patterns to be obtained under subambient conditions. In pharmaceutical systems, the greatest utility of the technique is to monitor the crystallization of solutes in frozen solutions. Conventionally, differential scanning calorimetry has been the most popular technique for the characterization of frozen systems. However, as mentioned earlier, this technique has some drawbacks (i) It does not enable direct identification of crystalline solid phase(s). Moreover, it is difficult to draw any definitive conclusions about the degree of crystallinity, (ii) The interpretation of DSC curves is very difficult if there are overlapping thermal events. Low temperature XRD was found to be an excellent complement to differential thermal analysis in the characterization of water-glycine-sucrose ternary systems. " ... 

Shalaev, E.Y. Malakhov, D.V. Kanev, A.N. Kosyakov, V.I. Tuzikov, F.V. Varaksin, N.A. Vavilin, V.I. Study of the phase diagram water fraction of the system water-glycine-sucrose by DTA and X-ray diffraction methods. Thermochim. Acta 1992,196 (1), 213-220. 

It has been found in a glyoxal/glycine model system by Velisek et at. (1976), in the reaction of L-rhamnose with ammonia by Shibamoto and Bernhard (1978), of glutamine with ribose by Ho and Chen (1999). Baltes and Bochmann (1987b) did not find the aldehyde when heating serine and threonine without sucrose. 

S2O3- + BrCHaCOOg- SaOiCHaCOOi + Brin such mixed solvent systems as C2H6OH + H2O, urea + H2O, glycine + H2O, and sucrose + H20. The observed slope is compatible with reasonable values of taj Vbj and rx- For the proton-catalyzed decomposition of the azo dicarbonate ion " whose rate-determining step is... 

It can be formed by a decarboxylative acylation of glycine followed by dehydration of the dienolic form of the intermediate compound. The product was isolated by Takken et al. (1976) when pyruvaldehyde and acetaldehyde reacted in closed vial glass systems at 90 °C with hydrogen sulfide and ammonia. It is also present in roasting mixtures of serine and/or threonine and sucrose (Baltes and Bochmann, 1987d). 

CH(0CH3)CH2) , polyvinylpyrrolidone (PVP) (-CH(NC4H70)CH2-) satisfy the criteria of NO-NO-NO systems (where N stands for negatively charged oxygen atoms due to its lone pair of electrons and O stands for vacant sites) but do not form intra- or intermolecular H bonds, also exclude Na" salts, sucrose, and glycine. 

Allfrey ei aU determined that there was a positive correlation between the RNA of the microsomes of mouse pancreas and the rate of protein synthesis in the tissue and a similar correlation between the quantity of RNA and the rate of N -glycine uptake by the protein of the microsomes. When the RNA was decomposed by ribonuclease, uptake of C -alanine by an in vitro system of microsomes plus mitochondria was impaired, indicating a dependence of protein synthesis on the intactness of the RNA. Treatment with ribonuclease was also found to eliminate the incorporation of radioactive leucine in lysed preparation of M. lyso-deikiticus prepared by treating sucrose suspensions of the organism with lysozjrme. ... 

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