Glyceritol 3-phosphate

The glyceritol phosphate (VI) has the 1-0-phospho-D (that is, 3-0-phos-pho-L) configuration since it is oxidized by Codehydrogenase I ( diphospho-pyridine nucleotide ) in the presence of glycerophosphate dehydrogenase (specific toward L-3-glycerophosphate ) to 1,3-dihydroxy-2-propanone phosphate. 

Working on this assumption, Baddiley and coworkers discovered a new group of polymers which they have named teichoic acids. These are mainly located in the cell wall and are polymers of ribitol phosphate or of glyceritol phosphate. ... 

Extracts prepared from whole cells of all such organisms contained a glyceritol phosphate polymer, even when no such polymer was present in the walls. This finding is in accordance with a previous report by Mitchell and Moyle that the cell envelope and the small particle fraction from Staphylococcus aureus contain a glyceritol phosphate. This observation could explain why Lactobacillus arabinosus contains cytidine glyceritol pyrophosphate (and not the corresponding teichoic acid) in the cell wall. 

A possible function of cytidine glyceritol pyrophosphate might be in the synthesis of glyceritol phosphate polymers, or in the condensation of glyceritol 3-phosphates with such organic bases as choline, ethanolamine, and serine, or with fatty acids. ... 

The structures of these cytidine nucleotides were confirmed by synthesis. Condensation of 1,2-0-isopropylidene-L-glyceritol 3-phosphate with cytidine 5-phosphate in the presence of dicyclohexylcarbodiimide, followed by careful acid hydrolysis of the isopropylidene group, yielded cytidine glyceritol pyrophosphate identical with the natural product. 

Glutaric acid, 2-oxo-, 253 Glyceritol, bis(sesquicarbonate), 127 carbonates, 128 1,2-carbonates, 112 calcium dioarbonate, 143 from polysaccharides, 87 D-, 1-phosphate, 215 3-phosphate, 213... 

Related to the interpretation of the effects of radiation on nucleic acids are the studies on the formation of labile phosphate esters in solutions of simple phosphates by irradiation. When glyceritol 1- and 2-phosphates are irradiated with 200 KV x-rays, inorganic phosphate is liberated. The former gives l,3-dihydroxy-2-propanone phosphate, and the latter, an acid-labile phosphate ester. " Detailed studies on methyl, ethyl, propyl, butyl, and amyl phosphates have indicated the mode of formation of such labile phosphate esters. Two reactions have been recognized ... 

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