Glycerin dehydration

Hyperosmolar drugs dehydrate local tissues, which causes irritation and increased peristalsis, with consequent evacuation of the fecal mass. Glycerin is a hyperosmolar drug. 

Glycerin Suppository [Laxative] Uses Constipation Action Hyperosmolar laxative Dose Adults. 1 adult supp PR PRN Feds. 1 infant supp PR daily-bid PRN Caution [C, ] Disp Supp SE D Interactions T Effects W/ diuretics EMS Monitor ECG and BP for signs of hypovolemia and electrolyte disturbances d/t D OD Unlikely but may cause severe D and dehydration symptomatic and supportive... 

The use of water-soluble bases may result in some irritation because, as they take up water and dissolve, they may produce slight dehydration of the rectal mucosa. They are widely used, however, and release the drug by dissolving and mixing with the aqueous body fluids. PEG suppository bases and glycerinated gelatin are the most popular in this class. 

Per each 100 U/mL 16mg/mL SC glycerin 1.50mg/mL phenol 1.72mg/mL m-cresol 19.6 pg/ mL zinc 1.25 mg/mL disodium hydrogen phosphate dehydrate ... 

Preparation and Properties of Copper(II) Hydroxide. 1. Add 0.5 ml of glycerin to a copper sulphate solution to prevent dehydration of... 

Can be prepd by heating glycerin with dehydrating agents such as KHS04, It is dangerous when exposed to heat or flame (Ref 5)... 

Dehydrating Value of Sulfuric (DVS) in Mixed Acids. In the process of nitration of aliphatic alcohols (such as glycerin, glycols, etc), it is necessary to know the exact composition of the nitrating acid. In the analysis of such acid, known as mixed acid (MA), the vollowing values must be detd TA (total acidity), TS (total sulfuric), IN (total nitric), AS (actual sulfuric),... 

Boric acid or orthoboric acid (commercially known as Optibor ) is a white triclinic crystal that is soluble in water (5.46 wt.%), alcohols, and glycerin. It is a weak acid and has a pH of 4 (saturated solution at room temperature). Upon heating in air to above 75°C, it loses part of its water of hydration to form metaboric acid (HBO at around 120°C-130°C. The metaboric acid can be further dehydrated to boric oxide at around 260°C-270°C. 

Acrolein was introduced by the French in January, 1916, a.s a filling for gas groniules and artillery. shell, in an effort to obtain an effective lacrimator which did not require bromine or acetone for its mumifactxire.. or< leiii is obtained by the dehydration of glycerine, by distilling it in the presfuice of potiissium bisulfate or crystallized magnesium sulfate ds a catalyst. 

Khaimar DB and Pangarkar VG. Dehydration of glycerin/water mixtures by pervaporation using homo and copolymer membranes. J. Am. Oil Chem. Soc. 2004 81(5) 505-510. 

Glycerin is used in a wide variety of pharmaceutical formulations including oral, ophthalmic, parenteral, and topical preparations. Adverse effects are mainly due to the dehydrating properties of glycerin. ... 

Propoxylated derivatives of sorbitol are used as the polyols in the formation of rigid polyurethane foams. Sorbitol can be dehydrated and esterified with stearic acid to give sorbitol mono- or tristearate. The ester then can be ethoxylated with about 20 ethylene oxide units to give an ethoxylated surfactant. Hydrolysis of sorbitol results with glycerin, which is used in the pharmaceutical and personal care products field [108,109],... 

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