Glutarates dimethyl

Dihydrogenated tallowethyl hydroxyethylmonium methosulfate Dimethicone propyl PG-betaine Dimethylaminoethyl methacrylate Dimethyl glutarate Dimethyl lauramine N,N-Dimethyl-N-lauric acid-amidopropyl-N-(3-sulfopropyl)-ammonium betaine... 

Cyclohexanol Cyclohexanone 3,4-Dichlorobenzotrifluoride DIethylene glycol dibutyl ether Dimethyl adipate Dimethyl glutarate Dimethyl succinate Dipropylene glycol butyl ether Dipropylene glycol t-butyl ether Dipropylene glycol ethyl ether... 

Dimethyl adipate Dimethyl glutarate Dimethyl succinate Ethyl hexanediol solvent, urethane coatings Methoxybutyl acetate Propylene glycol methyl ether acetate... 

The water solubiUty of glutaric acid fosters its toxicity. Glutaric acid is a known nephrotoxin. Renal failure has been documented ia rabbits adruinistered sodium glutarate subcutaneously (124). Dibasic ester (Du Pont), which contains primarily dimethyl glutarate, has low acute toxicity by inhalation and by ingestion, and is moderately toxic via dermal absorption. The acid is both a dermal and ocular irritant of humans. The ester is a severe skin irritant and may cause a rash ia humans (120). 

Porcine liver esterase (PLE) gives excellent enantioselectivity with both dimethyl 3-methylglutarate [19013-37-7] (lb) and malonate (2b) diester. It is apparent from Table 1 that the enzyme s selectivity strongly depends on the size of the alkyl group in the 2-position. The hydrolysis of ethyl derivative (2c) gives the S-enantiomer with 75% ee whereas the hydrolysis of heptyl derivative (2d) results in the R-monoester with 90% ee. Chymotrypsin [9004-07-3] (CT) does not discriminate glutarates that have small substituents in the 3-position well. However, when hydroxyl is replaced by the much bulkier benzyl derivative (Ic), enantioselectivity improves significantly. 

The addition of various Kolbe radicals generated from acetic acid, monochloro-acetic acid, trichloroacetic acid, oxalic acid, methyl adipate and methyl glutarate to acceptors such as ethylene, propylene, fluoroolefins and dimethyl maleate is reported in ref. [213]. Also the influence of reaction conditions (current density, olefin-type, olefin concentration) on the product yield and product ratios is individually discussed therein. The mechanism of the addition to ethylene is deduced from the results of adsorption and rotating ring disc studies. The findings demonstrate that the Kolbe radicals react in the surface layer with adsorbed ethylene [229]. In the oxidation of acetate in the presence of 1-octene at platinum and graphite anodes, products that originate from intermediate radicals and cations are observed [230]. 

Esters of higher diacids (e.g., dimethyl glutarates) have also proven quite informative. Thus, dimethyl 3-hydroxyglutarate (7.31) was hydrolyzed by PLE to the monoester of (S)-configuration (7.32), but the ee was low (ca. 20%) [55]. In contrast, a-chymotrypsin yielded the (R)-monoester with ee values of 60-70%, indicating large differences in the active sites of these... 

In Scheme A-1.1 [7] a comparison of a typical Diels-Alder reaction (butadiene + /7-benzoquinone) with a typical Weiss reaction (dimethyl 3-glutarate + glyoxal), in terms of AC, is shown. The stereochemistry of the products is implicit in the... 

Verma and Ghosh [72] desymmetrized a a-symmetric 3-dimethyl(phe-nyl)silyl substituted glutaric anhydride (127) with Evans oxazolidinone 128 (Scheme 32) as one of the key steps in their synthesis of (+)-preussin. 

Dimethyl 1,3-acetonedicarhoxylate Glutaric acid, 3-oxo-, dimethyl ester (8) Pentanedloic acid, 3-oxo-, dimethyl ester (9) (1830-54-2)... 

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