Glutaric acid, 3- -2,2-dimethyl

AI3-06026 DBE 5 Dimethyl giutarate Dimethyl pentanedioate EINECS 214-277-2 Glutaric acid, dimethyl ester HSDB 5789 NSC 58578 Pentanedioic acid, dimethyl ester. Liquid mp = -42.5° bp = 214°, bp2i = 109° d = 1.0876 soluble in CHCI3. very soluble in EtOH, Et20. 

The water solubiUty of glutaric acid fosters its toxicity. Glutaric acid is a known nephrotoxin. Renal failure has been documented ia rabbits adruinistered sodium glutarate subcutaneously (124). Dibasic ester (Du Pont), which contains primarily dimethyl glutarate, has low acute toxicity by inhalation and by ingestion, and is moderately toxic via dermal absorption. The acid is both a dermal and ocular irritant of humans. The ester is a severe skin irritant and may cause a rash ia humans (120). 

Dimethyl 1,3-acetonedicarhoxylate Glutaric acid, 3-oxo-, dimethyl ester (8) Pentanedloic acid, 3-oxo-, dimethyl ester (9) (1830-54-2)... 

Glularic Acid. Until 1990-1991 glularic acid was available commercially from DuPont as a by-product in the production of adipic acid. It is no longer available, but DuPont produces dimethyl glutaratc and mixtures of dimethyl succinate and dimethyl glutarate. as well as mixtures of dimethyl glutarate and dimethyl adipate. 

Dimethyl-D-arabinose has been obtained29 from 3-/J-D-galacto-pyranosyl-D-arabopyranose, obtained by the Wohl-Zempl6n degradation of lactose, by methylation and hydrolysis. Oxidation with nitric acid gave /9-hydroxy-aY-dimethoxy-D-arabo-glutaric acid, the amide of which was the enantiomorph of the product obtained from 2,4-dimethyl-L-arabinose. 

Glutaric acid, 30, 48 i8, 8-dimethyl-, 31, 40 3-ETHYL-3-METHYL-, 36, 28 Glutaric anhydride, ck-phenyl, 30, 81 Glycerol, 32, 72... 

This second step yields about 85% of the dimethyl adipate. The main by-products are about 10% dimethyl methyl glutarate, 3% dimethyl ethyl succinate, 1% dimethyl diethyl succinate, and 1% methyl pentanoates. The dimethyl adipate is isolated by distillation and converted to adipic acid by hydrolysis. 

Monomethyl ester of glutaric acid. See Methyl glutarate Monomethyl ether of hydroquinone. See Hydroquinone monomethyl ether Monomethyl glutarate. See Methyl glutarate Monomethylol dimethyl hydantoin. See MDM hydantoin Monooctadecylamine. See Stearamine Monoolein Monooleoylglycerol. See Glyceryl oleate Monopalmitate sorbitan. See Sorbitan palmitate Monopentaerythritol. See Pentaerythritol Monophenol. See Phenol... 

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