Glucose entrapment

PEG-modified glucose oxidase Analysis of glucose Entrapment of PEG-enzyme [26]... 

Entrapment of biochemically reactive molecules into conductive polymer substrates is being used to develop electrochemical biosensors (212). This has proven especially useful for the incorporation of enzymes that retain their specific chemical reactivity. Electropolymerization of pyrrole in an aqueous solution containing glucose oxidase (GO) leads to a polypyrrole in which the GO enzyme is co-deposited with the polymer. These polymer-entrapped GO electrodes have been used as glucose sensors. A direct relationship is seen between the electrode response and the glucose concentration in the solution which was analyzed with a typical measurement taking between 20 to 40 s. 

Figure 34 Chemical formula of y-cyclodextrin consisting of eight glucose molecules with adamantane as the guest entrapped within its hydrophobic cavity. Structures of a- and P-cyclodextrins will be similar but made up of six and seven (n = 6, 7) glucoses,...

Petersons pH probe also was modified in order to give a miniature fiber optic sensor potentially suitable for glucose measurements90. Kopelman et al.91 developed a fiber-optic pH nanosensor for physiological measurements using a dual-emission sensitive dye. The performance of a pH sensor was reported92. An unclad fiber was dip-coated with a thin layer of porous cladding within which a pH-sensitive dye was entrapped. The fundamental... 

The history of glucose enzyme electrodes starts with the first device developed in 1962 by Clark and Lyons from the Children Hospital in Cincinnati [3], Their first device relied on a thin layer of GOx entrapped over an oxygen electrode (via a semipermeable dialysis membrane), and monitoring the oxygen consumed by the enzyme-catalyzed reaction ... 

X.J. Wu and M.M.F. Choi, An optical glucose biosensor based on entrapped-glucose oxidase in silicate xerogel hybridised with hydroxyethyl carboxymethyl cellulose. Anal. Chim. Acta 514, 219-226 (2004). 

Y. Tatsu, K. Yamashita, M. Yamaguchi, S. Yamamura, H. Yamammoto, and S. Yoshikawa, Entrapment of glucose oxidase in silica gel by the sol-gel method and its application to glucose sensor. Chem. Lett. 36,1615-1618 (1992). 

J. Wang, D. Leech, M. Ozsoz, S. Martinez, and M.R. Smyth, One step fabrication of glucose sensors with enzyme entrapment within poly(ester-sulfonic acid), coatings. Anal. Chim. Acta 245, 139-143 (1991). 

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