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GLP-1 agonists

Glucagon-like peptide-1 (GLP-1) agonists Liraglutide Saxagliptin... [Pg.381]

Secretin inhibits postprandial gastrin release (thus decreasing gastric acid secretion) and increases pancreatic exocrine secretion (e.g. of bicarbonate). The secretin receptor (like the GLP-1 receptor and vasoactive intestinal peptide (VIP) receptor) acts via Gas and cAMP elevation. A plant agonist for the secretin receptor has been isolated from the Thai anti-ulcer plant Croton sublyratus (plau-loi) (Table 5.8). [Pg.167]

Navarro M, Rodriquez dF, Alvarez E, Chowen JA, Zueco JA, et al. 1996. Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells Evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake. J Neurochem 67 1982-1991. [Pg.226]

The Incretin Modulators - Incretin Mimetics (GLP-1 Receptor Agonists) and Incretin Enhancers (DPP-4 Inhibitors)... [Pg.111]

Therefore, it cannot be considered likely that the slight reduction in postprandial GLP-1 secretion in patients with type 2 diabetes has any immediate impact on glycemic control. Along the same lines, any administration of GLP-1 receptor agonists should not be simply considered a replacement of an essential hormone (e.g. GLP-1) that is lacking in patients with type 2 diabetes. [Pg.116]

GLP-l/GLP-1 receptor agonist concentration elevated Up to 24 h/day Predominantly for 3-6 h after meals, when secretion from endogenous sources is stimulated)... [Pg.122]

Thorens B, Porret A, Buhler L, Deng SP, Morel P, Widmann C. Cloning and functional expression of the human islet GLP-1 receptor. Demonstration that exendin is an agonist and exendin-(9-39) an antagonist of the receptor. Diabetes 1993 42 1678-1682. [Pg.132]

Exenatide is an incretin mimetic that acts as a glucagon-like peptide-1 (GLP-1) receptor agonist. This increases insulin secretion when glucose levels are high. It is given subcutaneously as an adjunct in type 2 diabetes in patients already receiving metformin, a sulphonylurea, or both. [Pg.468]

See other pages where GLP-1 agonists is mentioned: [Pg.97]    [Pg.442]    [Pg.442]    [Pg.1056]    [Pg.80]    [Pg.240]    [Pg.445]    [Pg.179]    [Pg.180]    [Pg.97]    [Pg.442]    [Pg.442]    [Pg.1056]    [Pg.80]    [Pg.240]    [Pg.445]    [Pg.179]    [Pg.180]    [Pg.451]    [Pg.471]    [Pg.507]    [Pg.131]    [Pg.131]    [Pg.132]    [Pg.132]    [Pg.141]    [Pg.542]    [Pg.401]    [Pg.388]    [Pg.136]    [Pg.635]    [Pg.13]    [Pg.217]    [Pg.97]    [Pg.32]    [Pg.285]    [Pg.145]    [Pg.247]    [Pg.117]    [Pg.117]    [Pg.117]    [Pg.120]    [Pg.120]    [Pg.120]    [Pg.121]    [Pg.122]    [Pg.32]    [Pg.365]    [Pg.312]   
See also in sourсe #XX -- [ Pg.112 , Pg.178 ]



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