Glaucoma drug induced

Open-angle glaucoma, secondary glaucoma, preoperatively to lower Intraocular pressure (IOP), edema due to CHF, drug-induced edema, centrencephalic epilepsy Glaucoma... 

Tripathi RC, Tripathi BJ, Haggerty C. Drug-induced glaucomas mechanism and management. Drug Saf 2003 26 749-767. Weinreb RN, Khaw PT. Primary open-angle glaucoma. Lancet 2004 363 1711-1720. 

Eighty-five percent of the 86 cases of mostly bilateral acute angle-closure glaucoma reported to the National Registry of Drug-Induced Ocular Side Effects by 2003 were noted to have occurred within the first 2 weeks of treatment initiation. Topiramate is considered to have certain OADRs in the form of abnormal vision, acute secondary angle-closure glaucoma, acute myopia, and suprachoroidal effusions. 

Postel EA, AssaUanA, Epstein DL. Drug-induced transient myopia and angle-closure glaucoma associated with supracUiary choroidal effusion. AmJ Ophthalmol 1996 122 110-112. 

Triptahi RC, Tripathi BJ, Haggerty C. Drug-induced glaucomas. Drug Saf 2003 26 749-767. 

Many drugs can increase IOP (Table 66-1). The potential to induce or worsen glaucoma depends on the type of glaucoma and on whether it is adequately controlled. 

Nadolol is noteworthy for its very long duration of action its spectrum of action is similar to that of timolol. Timolol is a nonselective agent with no local anesthetic activity. It has excellent ocular hypotensive effects when administered topically in the eye. Levobunolol (nonselective) and betaxolol (E -selective) are also used for topical ophthalmic application in glaucoma the latter drug may be less likely to induce bronchoconstriction than nonselective antagonists. Carteolol is a nonselective 13-receptor antagonist. 

Glaucoma (decreases formation of aqueous humor i IOP), acute mountain sickness (— - pulmonary and cerebral edema), metabolic alkalosis (e.g., thiazide-induced), elimination of acidic drugs (e.g., ASA, uric acid). 

In consonance with this, the drugs most widely used to treat glaucoma (for example, pilocarpine) are parasympathetomimetics, which induce miosis and... 

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