Glassware safety

Safe handling of laboratory glassware Safety showers and eye washes Technique of solid sample handling for IR spectroscopy... 

Special precautions. To avoid hydrolysis, it is advisable to use oven-dried glassware. Safety glasses should be worn during this experiment and all manipulations should be performed in a fume cupboard whilst wearing protective gloves. In particular, acetyl chloride causes severe bums and must be dispensed in a fumehood with appropriate gloves. 

The ETHOS MR is constituted of a multimode cavity very close to domestic oven with safety precautions. It can use standard glassware or glass (420 mL up to 2.5 bar) and polymer reactors (375 mL up to 200 °C and 30 bar) with magnetic stirring. The magnitude of microwave power available is 1 kW. The optical temperature sensor is immersed in the reaction vessel for quick response up to 250 °C. An infrared sensor is also available. A ceiling mounted is available in order to make connection with a conventional reflux system located outside the cavity or to ensure addition of reactants. 

The terms defined above are perhaps illustrated by using the example of the simple assay which we have mentioned before. The assay in Box 1.3 is laid out in the style of a SOP. This particular section of the operating procedure describes the assay itself but there would also be other sections in the procedure dealing with safety issues, the preparation and storage of the solutions used for extraction and dilution, the glassware required and a specification of the instrumentation to be used. 

CAUTTON Diazomethane is highly toxic and irritating. It is also a detonator and appropriate safety precautions and procedures should be used when handling this reagent (e.g., special glassware, blast shield,... 

On completion of the reaction, the material may be carefully degassed to remove any entrapped gasses and unreacted diisocyanate. Care must be taken to prevent foaming. Applying vacuum to the glassware does create the potential for it to implode. Suitable safety precautions must be taken. Table 3.2 indicates some typical time/temperature reaction conditions for some simple prepolymers. 

However, there are disadvantages to the base bath. First, it has some safety hazards. The alcohol is a potential fire hazard, and the bath s alkalinity is caustic to skin. The base bath is also a mild glass stripper. That is, instead of cleaning the glassware, it actually removes layers of glass (and any adjoining contamination). 

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