Glass sealing tests

Process controls include daily testing of water for injection (USP), conformation of fill doses and yields, checking and approving intermediate production tickets, and checking label identity and count. Finished product control includes all the tests necessary to ensure the potency, purity, and identity of the product. Parenteral products require additional tests, which include those for sterility, pyrogens, clarity, and particulate analysis, and for glass-sealed ampoules, leaker testing. 

A test method to evaluate the shear stress capability of a seal material is reported [36], An electrolyte-anode-electrolyte trilayer was glass sealed to two metal interconnect plates as shown in Figure 5.11. Shear testing was done in two different modes, constant loading rate and constant displacement rate, to determine the shear modulus and viscosity. 

Heat the drawn out part of the test tube until the glass melts, shape its end into a hook, and seal the tube. Spill 8-10 g of naphthalene onto the bottom of a wide bulbshaped test tube at least 40 cm long. Lower into it the sealed test tube for prepa- containing the phosphorus and fasten the hook-shaped end of the tube with copper wire to a glass... 

The volatile liquid (boiling point, 22° melting point, —10°) must now be distilled from the U tube and sealed in a glass tube. Select a strong tube of suitable diameter of soft glass, seal one end, and blow it out to rounded form like a test tube. At a height of the tube such that the volume below will be about twice that of the liquid to be preserved, soften the tube and draw it to a constriction of such diameter that the smallest tubing... 

Method. To the hydroxybiphenyl or phenol residue in a 2-ml glass-stoppered test-tube is added 0.2 ml of a solution of DNS-C1 (0.1% in acetone) and 30 jzl of 0.1 M sodium carbonate. The tube is sealed, gently shaken and incubated at 45 °C for 15-20 min. Two drops of 1N sodium hydroxide are added with shaking to destroy the excess of DNS-C1. 

All the components of the chamber that are in direct contact with the inlet and outlet air and the chamber atmosphere have to be constructed in such a way that they emit no relevant amounts of VOC under test conditions and show only a very small sink effect (see 2.1.3.2). Suitable materials for the walls of a chamber are electro-polished stainless steel and glass. Seals are especially critical components. As little of their surface as possible should come into contact with the chamber atmosphere. Additional appliances such as fans are also problematical. The TVOC background concentration should be lower than 10 pg/m the background concentration of single compounds should be lower than 2 pg/m. ... 

Hunadi R, Bilow N, Noack L. Determining corrosion tendencies of die-attach adhesives using the sealed glass tube test. Hybrid Circuit Technol. Apr. 1988. 

Hunadi, R., Bilow, N., andNoaek, L., Determining Corrosion Tendencies of Die-Attaeh Adhesives Using the Sealed Glass Tube Test, Hybrid Circuit Technol. (Apr. 1988)... 

The first method was employed with both neptunium and plutonium when these metals were tested for superconductivity down to temperatures of about 0.75°K [1]. Brass capsules of 1 mm wall thickness were used which had at one end platinum—glass seals through which the platinum wires for the current-potential measurement were passed. The active specimens were inserted into the capsules inside a glove box in which the electrical contacts were also made and in which the capsule was filled with helium gas and then sealed off. Prior to its introduction into the glove box, the capsule had been covered with a layer of shellac. After sealing off, the capsule was immersed in acetone which dissolved the shellac and in this manner the contamination sticking to the outside of the capsule was removed. 

Glass 73 Sealing Test 0.5 PSI Dry Air on Metal Side Air Sweep on NIO/YSZ Side... 

The microelectrode tip is then placed into water for about 20 seconds to check the glass seal. It is then examined under the microscope for water which might have leaked in by capillarity. Electrodes which absorb water are discarded. Those that are well sealed are placed on a plexiglass holder for filling and testing. 

Fig. 8.11 Isothermal-aged SCN-1 glass seals (between ceramic bilayers and aluminised SS441 substrate and contained between concentric YSZ layers) tested at a 750°C and b 800°C. (Chou and coworkers 2011)...

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