Gilead Sciences, tenofovir

USAN Tenofovir (TDF) Trade name Viread Gilead Sciences Launched 2001... [Pg.4]

Replication inhibitor Tenofovir PMPA Gel Gel Gilead Sciences Phases II/IIb... [Pg.844]

Tenofovir disoproxil fumarate (VIREAD, Gilead Sciences, Inc.) helps to block HIV-1 reverse transcriptase, which is an enzyme in the body that is needed for HIV-1 to multiply. [Pg.216]

Viread (Tenofovir disoproxil fumarate), Gilead Sciences International Ltd. UK Sinmnaiy of product characteristics, May 2007. [Pg.791]

Viread (Tenofovir disoproxil fumamte). Gilead Sciences, Inc. US Prescribii informatics. May 2007. [Pg.832]

Adenine itself was successfully incorporated into a number of pharmaceuticals, Adefovir dipivoxil, also known as bis-POM PMEA, with trade names Preveon and Hepsera, is used for the treatment of hepatitis B and herpes simplex virus infection. It is an orally administered nucleotide analog as a reverse transcriptase inhibitor (NRTI). Reverse transcriptase is an enzyme crucial to viral production. A second NRXI that contains adenine is Tenofovir disoproxil fumarate (TDF), which has been used in the treatment of HIV/AIDS and hepatitis B. TDF is a prodrug of tenofovir (also known as PMPA) designed to improve absorption and cell permeability of the active moiety under the trade name Viread. Both adefovir dipivoxil and TDF are marketed by Gilead Sciences. [Pg.571]

Tenofovir Gilead Sciences 9.3 129 Reverse transcriptase inhibitor HIV, hepatitis B... [Pg.212]

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