Geodon

Ziprasidone Risperdal Consta Geodon 1, 2, 3, 4 mg Oral solution 1 mg/mL Long-acting injectable 25, 37.5, 50 mg Capsule 20, 40, 60 80 mg 40-160 mg/day in divided doses is not approved at present for bipolar disorder... 

Ziprasidone Geodon Capsule 20, 40,60, 80 mg Calcium channel blockers Not FDA approved for bipolar disorder 40-160 mg/day in divided doses ... 

Ziprasidone (Geodon). Ziprasidone is indicated for the treatmet of acute mania with typical doses of 40-80 mg twice a day. Ziprasidone is well tolerated, with the most common side effects being sedation, extrapyramidal symptoms, and akathisia. Low magnesium or potassium may cause potentially serious cardiac conduction problems with ziprasidone. 

Atypical antipsychotics may be helpful in managing the delusions and agitated behavior that can accompany dementia. These medications, include risperidone (Risperdal), quetiapine (Seroquel), ziprasidone (Geodon), aripiprazole (Abilify), and olanzapine (Zyprexa). All antipsychotics, typical and atypical, appear to increase the risk of death in patients with dementia and psychosis. This appears as a warning in the package inserts of the newer drugs. A prudent approach is to discuss this risk with the caregiver, use the lowest effective dose, and monitor for effectiveness. 

Among these choices, bnspirone is preferred if the patient is also experiencing anxiety. If the patient is depressed and agitated, a SSRI should be tried first. Second line choices inclnde carbamazepine (Tegretol) or one of the atypical antipsychot-ics—ziprasidone (Geodon), risperidone (Risperdal), olanzapine (Zyprexa), quetiap-ine (Seroquel), or aripiprazole (Abilify) can be tried. If psychotic symptoms are present, one of the atypical antipsychotics should be tried first. 

The so-called atypical antipsychotics represent one of the newest options for managing disruptive behavioral syndromes. Because they have yet to be studied in patients who have suffered a TBI, we certainly cannot recommend the atypical antipsychotics for routine first-line use. Nevertheless, an atypical antipsychotic might prove helpful when other medicines aren t providing satisfactory results in the management of severe behavioral disturbances. Ziprasidone (Geodon) is available in an injectable form that we have found to be particularly helpful in TBI patients. 

Receptor-Binding Studies. Among the newer atypical antipsychotics, ziprasidone (Geodon) has a distinctive pharmacological profile ( Fig. 5-2). Binding studies indicate that ziprasidone has a high affinity for D 2 receptors, approximately equal to that of risperidone. In vitro, ziprasidone ... 

CAPTISOL ) Ziprasidone IM Europe, Japan United States, Geodon /... 

USAN Ziprasidone Trade Name Geodon Company Pfizer... 

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