Genome analysis sequencing

It should be possible to extend the DNA microarray-binding experiment to whole-genome analysis of transcription factor binding sites. The authors suggest that a microarray spotted with 12,000 one-kilobase sequences would span the entire Saccharomyces cerevisiae genome (Bulyk et al., 2001). Such an array could be used to characterize the sequence specificity of S. cerevisiae transcription factors. These experiments would be useful for predicting functions of previously uncharacterized transcription... 

The Genome International Sequencing Consortium. Initial sequencing and analysis of the human genome. Nature 2001 409 860-921. 

Array-based comparative genomic hybridization (a-CGH) is a genomic analysis system that allows identification of alterations in DNA sequence and copy number, with a potential goal of individualized diagnosis and targeted cancer therapy.35,36 A number of reports have described application of a-CGH to DNA extracted from FFPE tissues, with variable results.35,37 38... 

Pawlowski, K, Zhang, B., Rychlewski, L., and Godzik, A. (1999). The Helicobacter pylori genome from sequence analysis to structural and functional predictions. Proteins 36, 20-30. 

DNA IN CHROMATIN FROM GENOME-WIDE SEQUENCE ANALYSIS TO THE MODELING OF REPLICATION IN MAMMALS... 

DNA IN chromatin FROM GENOME-WIDE SEQUENCE ANALYSIS 225 DNMTl Lamine B2 globine... 

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