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Longevity genes

Chrousos G The glucocorticoid receptor gene, longevity, and the highly prevalent complex disorders of western societies. Am J Med 2004 117 204. [PMID 15300973]... [Pg.892]

De Benedictis G, Falcone E, Rose G, et al. DNA multiallelic systems reveal gene/ longevity associations not detected by diallelic systems. The APOB locus. Hum Genet 1997 99 312-318. [Pg.207]

Larsen, P.L., Albert, P.S. and Riddle, D.L. (1995) Genes that regulate both development and longevity in Caenorhabditis elegans. Genetics 139, 1567—1583. [Pg.289]

Brattstrom L, Zhang Y, Hurtig M et al. A common methylenetetrahydrofolate reductase gene mutation and longevity. Atherosclerosis 1998 141 315-319. [Pg.308]

The ACE gene encodes two isozymes (somatic ACE isozyme and germinal ACE isozyme). ACE is a membrane-bound enzyme on the surface of vascular endothelial cells that also circulates in plasma and shows great individual variability determined by an I/D polymorphism in intron 16 of the ACE gene (ACE-I/D polymorphism). More than 160 ACE polymorphisms have been reported, 34 of which are located in coding regions, and 18 are missense mutations (606). ACE-related polymorphic variants have been associated with hypertension, atherosclerosis, stroke, left ventricular hypertrophy, chronic renal failure in IgA nephropathy, Henoch-Schonlein purpura nephritis, mechanical efficiency of skeletal muscle, intracranial aneurysms, susceptibility to myocardial infarction, diabetic nephropathy, AD, and longevity (12,606,607). [Pg.312]

Kaeberlein, M., McVey, M. and Guarente, L. (1999) The S1R2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms. Genes S, Development, 13, 2570-2580. [Pg.236]

Miyazaki R, Ichiki T, Hashimoto T, Inanaga K, Imayama I, Sadoshima J, Sunagawa K. 2008. SIRT1, a longevity gene, downregulates angiotensin II type 1 receptor expression in vascular smooth muscle cells. Arterioscler Thromb Vase Biol. [Pg.212]

Vina J, Sastre J, Pallardo FV, Gambini J, Borras C. 2008. Modulation of longevity-associated genes by estrogens or phytoestrogens. Biol Chem 389 273-277. [Pg.247]

Hall SS. 2003. Longevity research. In vino vitalis Compounds activate life-extending genes. Science 301 1165. [Pg.323]

Calabrese V, Colombrita C, Scapagnini G, Calvani M, Giuffrida Stella AM. Butterfield DA. 2006a. Acetylcamitine and cellular stress response Role in nutritional redox homeostasis and regulation of longevity genes. J Nutr Biochem 17 73-88. [Pg.445]

Hypothetical Classification of Longevity Genes or Their Alternatives0... [Pg.187]

Genes that influence differences in life-span among species (e.g., longevity-enabling genes)"... [Pg.187]

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See also in sourсe #XX -- [ Pg.360 ]



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