Genes, characterizations

M32. Mukai, T Yatsuki, H., Arai, Y., Joh, K., Matsuhashi, S and Hori, K., Human aldolase B gene Characterization of the genomic aldolase B gene and analysis of sequences required for multiple polyadenylations. J. Biochem. 102, 1043-1051 (1987). 

The three Squat (sqt) mutants have a characteristic dominant-dumpy/ recessive-roller phenotype, and of the two genes characterized sqt-1 and sqt-3), both encode cuticle collagens (Kramer, 1997). 

Rushmore, T.H. and Pickett, C.B. (1990) Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants. Journal of Biological Chemistry, 265, 14648-14653. 

Lo Piero AR, Puglisi I, Petrone G (2006) Gene characterization, analysis of expression and in vitro synthesis of dihydroflavonol 4-reductase from [Citrus sinensis (L.) Osbeck]. Phytochemistry 67(7) 684-695... 

Zurita, M., Bieber, D., Ringold, C. and Mansour, T.E. (1 988) cDNA cloning and gene characterization of the mitochondrial large subunit (LSU) rRNA from the liver fluke Fasciola hepatica. Evidence of heterogeneity in the fluke mitochondrial genome. Nucleic Acids Research 16, 7001-7012. 

Nunes, C.P., Zaha, A., Gottstein, B., Muller, N. and Siles-Lucas, M.del M. (2004) 14-3-3 gene characterization and description of a second 14-3-3 isoform in both Echinococcus granulosus and E. multilocularis. Parasitology Research 93, 403-409. 

Favreau LV, Pickett CB. 1993. Transcriptional regulation of the rat NAD(P)H quinone reductase gene. Characterization of a DNA-protein interaction at the antioxidant responsive element and induction by 12-O-tetradecoylphorbol 13-acetate. J Biol Chem 268 19875-19881. 

Liu W., Jiao H., Murray N. C., O Conner M. and Roelofs W. L. (2002) Gene characterized for membrane desaturase that produces ( )-11 isomers of mono- and diunsaturated fatty acids. Proc. Natl. Acad. Sci. USA 99, 620-624. 

Abraham D., Lofstedt C. and Picimbon J. F. (2003) Molecular evolution and gene characterization of Grpl and Grp 2 Pheromone Binding Proteins in moths. Genetics (manuscript submitted for publication). 

Searles, R.P., Midson, C.N., Nipper, V.J., and Machida, C.A. 1995. Transcription of the rat Pj-adrenergic receptor gene. Characterization of the transcript and identification of important sequences. J. Biol. Chem. 270 157-162. 

Anderson, O.D., Hsia, C.C., Torres, V. 2001. Wheat y-gliadin genes Characterization of ten new sequences and further understanding of y-gliadin gene family structure. TheorAppl Genet 103 323-330. 

Although apparently not noticed by I.ander et al. (2001), their results on intron size (see Fig. 5.3) confirm the existence of two classes of genes characterized by distinctly different intron sizes (Caiels and Bcrnardi, 2000) in that they show a sharp transition with a midpoint at about 45% GC, again in agreement with (he boundary between the genome core and the empty quarter. 

Wakeland The nice thing about the Sanroque study in human is that you could demonstrate that at least one of these alleles does have a phenotype in mice quite consistent with what is seen in the original mutation. Is there any way you could do a similar thing with your alleles One of the problems of these rare variants is that you end up with one or two families. The power is simply insufficient to map into a tight critical region. In the end, you find this gene, characterize the mutation, and make the case for the idea that it causes this disease, but it can be difficult to prove this to a statistical geneticist. 

DNA from the capsule filters was extracted for whole community 16S rDNA and urease gene characterization using a umdified sucrose lysis filter extraction method (P, 10). Briefly, 40 mL of lysis buffer (20 mM EDTA, 400MNaCl, 50 mM Tris, and 0.75 M sucrose, pH 9), 4 mL 10% SDS, and... 

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