Generation of radical species

The Barton-McCombie process is an important synthetic tool for the generation of radical species. Me3SiO-(SiHMeO)n-SiMe3 works as a stoichiometric reductant in the tin-catalyzed reaction since Bu3Sn(OPh) is reduced to Bu3SnH as shown in Scheme 31 [71]. 

Salkar et al. [51] reported the formation of amorphous silver nanoparticles of approximately 20 nm size by the sonochemical reduction of an aqueous solution of silver nitrate in an atmosphere of argon-hydrogen [in the ratio of 95 5] at 10°C. Formation of silver nanoparticles, according to them was through the generation of radical species - as a primary reaction. 

The generation of radical species in the two one-electron reduction steps can result in a complex profile of reaction products, including trimers and higher oligomers that may themselves act as reducing substrates in subsequent turnovers. Several of the functions of PX are related to the formation of these radical products. Among these functions,... 

The reactivity of the surface such as the generation of radical species and reaction with organic molecules. 

GENERATION OF RADICAL SPECIES BY SINGLE-ELECTRON-TRANSFER REACTIONS AND THEIR APPLICATION TO THE DEVELOPMENT OF SYNTHETIC REACTIONS... 

Generation of Radical Species by Single-Electron-Transfer... 

Photochemical Generation of Radical Species from a-Stannyl Sulfides and Ethers... 

Ultrasound is known for its capacity to promote heterogeneous reactions (Ley and Low, 1989) mainly through greatly increased mass transport, interfacial cleaning and thermal effects. In addition, homogeneous chemical reactions have been reported to be modified (Suslick et ai, 1983 Luche, 1990 Colarusso and Serpone, 1996) for example the sonochemical generation of radical species in aqueous media is important in environmental detoxification (Kotronarou et al., 1991 Serpone et al., 1994). 

Iron being a redox-active metal, it most hkely exerts its toxic effects through the generation of hydroxyl radical or by generation of ferryl ion. In iron loaded condition, there is generation of radical species leading to hpid peroxidation. Lipid peroxidation of cellular membrane would have deleterious effects on their function and hence on the function of the cell. There is also irreversible oxidation of ascorbic acid. Deficiency of ascorbic acid can lead to a reduction in the amount of iron available for erythropoiesis. 

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