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Generation of Ag-Specific Cell-Mediated Responses

BALB/c mice were immunized subcutaneously with 50-100 4g of the above constructs dissolved only in 100 4l of sterile PBS and were boosted at 21-day intervals. Spleen cells were harvested, incubated with 150nM of the HBsAg CTL [Pg.684]

Although this mechanism of action for the molecular adjuvant still needs to be effectively characterized and is a major focus of research in our laboratory, it may suggest a novel pathway of exogenous MHC class I Ag presentation such [Pg.685]


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Cell mediated

Cell specificity

Cell-mediated response

Response cells

Specific response

Specifications, cell

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