Gene/Genes

Promoter gene gene gene gene gene... 

Target gene Gene product Ribozyme-induced change of function... 

Gene Gene Size (kb) Number of Introns mRNA Size (kb)... 

Food Company/year Gene, gene product, or gene fragment Source Intended effect... 

DNA mismatch repair genes Genes that identify and correct errors in DNA base pairs during DNA replication. Mutations in the mismatch repair genes can lead to cancer by allowing abnormal cells to continue to grow. 

Tumor suppressor genes Genes that normally restrain cell growth, but when missing or inactivated by mutation, allow cells to grow uncontrolled and tumors to form. 

T17. Tomatsu, S., Kobayashi, Y., Fukumaki, Y., Yubisui, T., Orii, T., and Sakaki, Y., The organization and the complete nucleotide sequence of the human NADH-cytochrome b5 reductase gene. Gene 80,353-361 (1989). 

Porter, S., and Mintz, B. (1991). Multiple alternatively spliced transcripts of the mouse tyrosinase-encoding gene. Gene 97 277-282. 

Inoue, C., Sugawara, K., and Kusano, T., Thiobacillus ferrooxidans mer operon Sequence analysis of the promoter and adjacent genes, Gene, 96 (1), 115-120, 1990. 

Kucho, K.-I., Y. Tsuchiya, Y. Okumoto et al. (2004). Construction of unmodified oligonucleotide-based arrays in the thermophilic cyanobacterium Thermosynechococcus elongatus BP-1 Screening of the candidates for circadianly expressed genes. Genes Genet Syst 79 319-329. 

Stewart MJ, Dipple KM, Stewart TR, Crabb DW. The role of nuclear factor NF-Y/CP1 in the transcriptional regulation of the human aldehyde dehydrogenase 2-encoding gene. Gene 1996 173 155-161. 

Xu, J., et al., "Genomewide Screen and Identification of Gene-Gene Interactions for Asthma-Susceptibility Loci in Three U.S. Populations Collaborative Study of the Genetics of Asthma," Am.. Hum. Genet., 68, 1437-1446 (2001). 

There must be direct and demonstrated correlation between the disease and the defect in the gene/gene product. 

Table V shows a classification of binary relations gene-gene relations, protein-protein relations, and other molecule-molecule relations. Different sets of binary relations can then be related to different types of graphs. For example, the generalized protein-protein interaction network is equivalent to a set of protein-protein binary relations. The KEGG metabolic pathway is a generalized protein-protein network, but it is also a network of chemical compounds that can be converted to a set of com-...

Gene-gene relation Sequence similarity/orthology Positional correlation in genome Expression similarity (coregulation of genes)... 

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