Gene expression signatures

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Lamb, J., Crawford, E.D., Peck, D., et al. (2006) The Connectivity Map using gene-expression signatures to connect small molecules, gene, and disease. Science, 313, 1929-1935. 

Semizarov D, Frost L, Sarthy A et al (2003) Specificity of short interfering RNA determined through gene expression signatures. Proc Natl Acad Sci USA 100 6347-6352... 

Klein CA. Gene expression signatures, cancer cell evolution and metastatic progression. Cell Cycle 2004 3 29-31. 

Chung YJ, Kim TM, Kim DW et al. Gene expression signatures associated with the resistance to imatinib. Leukemia 2006 20 1542-1550. 

Frank O, Brors B, Fabarius A et al. Gene expression signature of primary imatinib-resistant chronic myeloid leukemia patients. Leukemia 2006 20 1400-1407. 

Sotiriou C, Neo SY, McShane LM et al. Breast cancer classification and prognosis based on gene expression profiles from a population-based study. Proc Natl Acad Sci USA 2003 100 10393-10398. van de Vijver MJ, He YD, van t Veer LJ et al. A gene-expression signature as a predictor of survival in breast cancer. NEnglJMed2002 347 1999-2009. 

Chang HY, Nuyten DS, Sneddon JB et al. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci USA 2005 102 3738-3743. 

Naderi A, Teschendorff AE, Barbosa-Morais NL et al. A gene-expression signature to predict survival in breast cancer across independent data sets. Oncogene 2007 26 1507-1516. 

Lamb J, Crawford ED, Peck D et al. The Cormeetivity Map using gene-expression signatures to cormect small molecules, genes, and disease. Science 2006 313 1929-1935. 

Troester MA, Hoadley KA, Parker JS et al. Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast eell lines. Environ Health Perspect 2004 112 1607-1613. Yang Y, Blomme EA, Waring IF. Toxicogenomics in drug discovery from preclinical studies to elin-ical trials. Chem Biol Interact 2004 150 71-85. 

Hieronymus H, Lamb J, Ross KN et al. Gene expression signature-based ehemieal genomic prediction identifies a novel class of HSP90 pathway modulators. Cancer Cell 2006 10 321-330. 

Fielden, M.R., Eynon, B.P., Natsoulis, G., Jarnagin, K., Banas, D. and Kolaja, K.L. (2005) A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity. Toxicol. Pathol.,... 

Lu Y, Yao R, Yan Y, Wang Y, Hara Y, Lubet RA, You M. 2006b. A gene expression signature that can predict green tea exposure and chemopreventive efficacy of lung cancer in mice. Cancer Res 66 1956-1963. 

S, Rutgers ET, Friend SH, Bernards R. A gene-expression signature as a predictor of survival in breast cancer. N Engl J Med 2002 347 1999-2009. 

Weisz A, Identification of the gene expression signature which characterizes human breast cancer cells response to estrogen, Proceedings of Second International Cancer Congress Translational Research in Cancer, Rovigo, p. 83, 2001. 

Almstrup K, Ottesen AM, Sonne SB, Hoei-Hansen CE, Leffers H, Rajpert-De Meyts E, et al. Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ. Cell Tissue Res 2005 322(1) 159-165. 

Chang HY, Sneddon JB, Alizadeh AA et al. Gene Expression Signature of Fibroblast Scram Response Predicts Human Cancer Progression Similarities between Tumors and Wounds. PLoS Biol 2004 2(2) E7. 

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