Duplication, gene

McLachlan, A.D. Gene duplications in the structural evolution of chymotrypsin. J. Mol. Biol. 128 49-79,... 

FIGURE 10.18 A model for the structure of the a-factor transport protein in the yeast plasma membrane. Gene duplication has yielded a protein with two identical halves, each half containing six transmembrane helical segments and an ATP-binding site. Like the yeast a-factor transporter, the multidrug transporter is postulated to have 12 transmembrane helices and 2 ATP-binding sites. 

Devonshire, A.L. and Sawicki, R.M. (1979). Insecticide resistant Afyz 5 persicae as an example of evolution by gene duplication London. Nature 280,140-141. 

Higher organisms often elaborate several physically distinct versions of a given enzyme, each of which catalyzes the same reaction. Like the members of other protein families, these protein catalysts or isozymes arise through gene duplication. Isozymes may exhibit subtle differences in properties such as sensitivity to... 

Gallagher, C.E. et al.. Gene duplication in the carotenoid biosynthetic pathway preceded evolution of the grasses (Poaceae). Plant Physiol. 135, 1776, 2004. 

The evolutionary development of starter types, from which proteins later evolved via gene duplication and mutation... 

Homo sapiens (compared to Drosophila melanogaster) Large-scale gene duplications with substantial expansion of genes involved in acquired immune response (B cells, T cells, major histocompatibility complex genes, cytokines, chemokines and their receptors), plasma proteases (complement and hemostatic proteins), proteins associated with apoptotic regulation and proteins related to neuronal network formation and electrical coupling... 

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