Gene device

New cells, Genes Devices Growth Factors Delivery methods Cell Tracking Functional Analyses... 

A gene gun is a device to introduce DNA into cells in vivo. The DNA is attached to gold particles, which are introduced under high velocity into the target tissue. 

Hatakeyama H, Akita H, Harashima H (2011) A multifunctional envelope type nano device (MEND) for gene delivery to tumours based on the EPR effect a strategy for overcoming the PEG dilemma. Adv Drug Deliv Rev 63 152-160... 

DEVIC, M., GUILLEMINOT, J., DEBEAUJON, I., BECHTOLD, N BENSAUDE, E., KOORNNEEF, M PELLETIER, G., DELSENY, M., The BANYULS gene encodes a DFR-like protein and is a marker of early seed coat development, Plant J., 1999, 19, 387-398. 

Biomedical devices, 3 707, 709 cardiovascular devices, 3 709-721 orthopedic devices, 3 721-735 tantalum, 24 327 Biomedical research, 9 43 radiotracers in, 21 279-280 transgenic and gene-targeted mice for, 12 466-167... 

M. Eggers and D.A. Ehrlich, A review of microfabricate devices for gene based diagnostics, Hematol. Pathol., 9 (1995) 1-15. 

ICH guidelines specifically require three genotoxicity assays for all devices (see Table 6.2). The assays should preferably evaluate DNA effects, gene mutations and chromosomal aberrations, and two of the assays should preferably use mammalian cells. Guidance for providing tests for selection to meet these needs are the OECD guidelines, which include 8 in vitro and 7 in vivo assays. 

Seeman NC (2005). From genes to machines DNA nanomechanical devices. Trends Biochem. Sci. 30 119-125. 

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