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Gene delivery antisense oligonucleotides

After a comprehensive introduction, the basic PK/PD properties of peptides, monoclonal antibodies, antisense oligonucleotides and gene delivery vectors are reviewed. In the second part, the book covers a number of challenges and opportunities in this field such as bioanalytical methods, bioequivalence and pulmonary delivery. The text finishes with a detailed presentation of some real-life examples and case studies which should be of particular interest to the reader and integrate many of the concepts presented earlier in the text. [Pg.410]

Following a short introduction, the book is structured into three sections The Basics section discusses individually the pharmacokinetics of peptides, monoclonal antibodies, antisense oligonucleotides and gene delivery vectors. The subsequent Challenges and Opportunities section includes more detailed considerations on selected topics, including technical challenges such as bioanalytical... [Pg.412]

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See also in sourсe #XX -- [ Pg.252 , Pg.255 , Pg.257 ]



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