Gelatin scaffolds

In biomedical applications, transglutaminases have been used for tissue engineering materials such as enzymatically crosslinked collagen [60-63] or gelatin scaffolds [64-69]. Even melt-extruded guides based on enzymatically crosslinked macromolecules for peripheral nerve repair have been reported [70]. 

Kang, H.W. Tabata, Y. Ikada, Y. Fabrication of porous gelatin scaffolds for tissue engineering. Biomaterials 1999, 20, 1339-1344. 

Nanoscaled PCL and PCL/gelatin fibrous scaffolds with immobilized epidermal growth factor (EGF) were prepared for the purpose of wound-healing treatments [80]. The tissue scaffolds were fabricated by electrospinning and the parameters that affect the electrospinning process were optimized. In this study, the fiber diameters were 488 114 nm and 663 107 nm for PCL and PCL/gelatin scaffolds, respectively, and the porosities were calculated as 79% for PCL and 68% for... 

Highly porous chitosan-gelatin scaffolds by combining three different fabrication techniques, i.e., rapid prototyping, microreplication, and freeze-drying Natural nanofibrous scaffolds by electrospinning of GC into nanofibers... 

Adekogbe I, Ghanem A (2005) Fabrication and characterization of DTBP-crosslinked chitosan scaffolds for skin tissue engineering. Biomaterials 26 7241-7250 Liu FI, Fan FI, Cui Y et al (2007) Effects of the controlled-released basic fibroblast growth factor from chitosan-gelatin microspheres on a chitosan-gelatin scaffold. Biomacromolecules 8 1446-1455... 

Fig. 9 Fabrication process for porous chitosan/gelatin scaffold with well-organized channels and chambers [69]...

Awad, H. A., Wickham, M. Q., Leddy, H. A., Gimble, J. M., GuUak, P. Chondrogenic differentiation of adipose-derived adult stem cells in agarose, alginate, and gelatin scaffolds. Biomaterials. 2004, 25, 3211-3222. 

In another study Feng et al. [86] presented the stmcture and properties of new thermoforming bionanocomposites based on chitin whiskers-graft-polycaprolac-tone. The synthesized material was characterized by FTIR, SEM, TEM and XRD. The surface and mechanical properties were also determined and discussed. Ha-riraksapitak et al. [87] prepared a neat hyaluronan-gelatin scaffolds and chitin-whisker-reinforced hyaluronan-gelatin scaffolds. The obtained cylindrical scaffolds obtained were about 10 mm in diameter and 2 mm in height, whereas the disc-shaped scaffolds were about 1 mm in thickness these were later cut into a desired shape and size for the mechanical property assessment. 

Pankongadisak P, Ruktanonchai UR, Supaphol P, Suwantong O. Development of silver nanoparticles-loaded calcium alginate beads embedded in gelatin scaffolds for use as wound dressings. Polymer Int 2015 64(2) 275-83. 

S.J. (2012) The effect of controlled release of PDGF-BB from heparin-conjugated electrospun PCL/gelatin scaffolds on cellular bioactivity and infiltration. i)/omateriafs, 33, 6709-6720. 

Liu, X., and P.X. Ma. 2009. Phase separation, pore stmcture, and properties of nanofibrous gelatin scaffolds. Biomaterials 30(25) 4094-4103. 

Huang, Y., Onyeri, S., Siewe, M., Moshfeghian, A., Madihally, S.V., 2005. In vitro characterization of chitosan-gelatin scaffolds fortissue engineering. Biomaterials 26,7616—7627. 

Thein-Han WW, Saikhun J, Pholpramoo C, Misra RDK, Kitiyanant Y (2009) Chitosan-gelatin scaffolds for tissue engineering physico-chemical properties and biological response of buffalo embryonic stem cells and transfectant of GFP-buffalo embryonic stem cells. Acta Biomater 5(9) 3453-3466... 

Huang Y, Onyeri S, Siewe M, Moshfeghian A, MadihaUy SV. In vitro characterization of chitosan-gelatin scaffolds for tissue engineering. Biomaterials 2005 26 7616. 

Powell, H. M. and S. T. Boyce. 2008. Fiber density of electrospun gelatin scaffolds regulates morphogenesis of dermal-epidermal skin substitutes. J Biomed Mater Res A 84 1078-86. 

Kang, H. G., Kim, S. Y., and Lee, Y. M. 2006. Novel porous gelatin scaffolds by overrun/particle leaching process for tissue engineering applications. / Biomed Mater Res B Appl Biomater 79B 388-97. 

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