Pharmaceutical gelatin

Phaltan. See N-Trichloromethylthio phthalimide Phantolld. See Acetyl hexamethyl indan Pharma-Carb . See Calcium carbonate Pharmacol 101, Pharmacel 102, Pharmacel 105, Pharmacel 112, Pharmacel 200. See Microcrystalline cellulose Pharmacel XL. See Croscarmellose sodium Pharmaceutical Gelatin. See Gelatin Pharmaceutical Lanolin. See Lanolin Pharma-Gel . See Corn (Zea mays) starch Pharmasolve . See N-Methyl-2-pyrrolidone Pharmasorb Colloidal Pharmaceutical Grade. See Attapulgite... 

Protein-based plastics have been used, alone or in mixtures, to obtain edible films and eoatings. They have been used to protect pharmaceuticals and to improve the shelf life of food products. Some commercialization of protein films has been realized in collagen sansage casing, gelatin pharmaceutical capsules and corn zein protective coatings for nutmeats and candies [71]. 

Uses of gelatin are based on its combination of properties reversible gel-to-sol transition of aqueous solution viscosity of warm aqueous solutions abUity to act as a protective coUoid water permeabUity and insolubUity in cold water, but complete solubUity in hot water. It is also nutritious. These properties are utilized in the food, pharmaceutical, and photographic industries. In addition, gelatin forms strong, uniform, clear, moderately flexible coatings which readily sweU and absorb water and are ideal for the manufacture of photographic films and pharmaceutical capsules. 

Gelatinous boehmite, called alumina gel in commeicial use, is used in the piepaiation of adsorbents, desiccants (qv), catalysts, and catalyst supports (see Catalysts, SUPPORTBd). A significant amount is used in pharmaceutical preparations. 

Gelatin has long been used as a food ingredient (e.g., gelling and foaming agent), in the preparation of pharmaceutical products (e.g., soft and hard capsule, microspheres), in the... 

Protective colloids can be divided into synthetic and natural materials. Table 3 classifies the pharmaceutical gums, thickeners, and other hydrophilic polymers according to their origins [72]. Protective colloids of natural origin, such as gelatin, acacia, and tragacanth, have... 

One disadvantage of soft gelatin capsules is that such products often must be contracted out to a limited number of firms having the necessary filling equipment and expertise. Materials must be shipped to the soft gelatin capsule facility, and products must be shipped back to the pharmaceutical manufacturer for final packaging and distribution. Additional quality control measures may be required. 

BE Jones. Hard gelatin capsules and the pharmaceutical formulator. PharmTechnol9(9) 106-108,110,112,1985. 

Y Miyake, A Shimoda, T Jasu, M Furukawa, K Nesuji, K. Hoshi. Packing properties of pharmaceutical powders into hard gelatin capsules. Yakuzaigaku 34 32, 1974. 

IG Jolliffe, JM Newton, JK Walters. Theoretical considerations of the filling of pharmaceutical hard gelatine capsules. Powder Tech 27 189-195, 1980. ... 

IR Berry. One-piece, soft gelatin capsules for pharmaceutical products. Pharm Eng 5(5) 15—19, 1985. 

Cortesi, R., Esposito, E., Menegatti, E., Gambari, R., Nastruzzi, C., Gelatine micro-spheres as a new approach for controlled delivery of synthetic oligonucleotides and PCR-generated fragments, International Journal of Pharmaceutics, 1994, 105, 181-186. 

As gelatin is a common food additive with applications in the pharmaceutical industry, its introduction into foreign protein production systems may generate fewer regulatory concerns than other biopolymers. 

---