Gastrointestinal transit time, liver

Patients with liver disease may have an increased gastrointestinal transit time [3]. These patients may benefit from taking a pro-kinetic agent, as normalisation of gastrointestinal motility will reduce the time available for the absorption of nitrogenous compounds that may precipitate encephalopathy. The use of pro-kinetic agents has also been shown to reduce intestinal bacterial overgrowth in patients with cirrhosis [4-6]. 

SPIOs are used for gastrointestinal tract, liver, and spleen imaging and take advantage of the natural clearance of the RES, the transit time through the gut or preferential uptake by specific cells. The most promising uses of SPIOs are to improve the sensitivity of detection and localization of primary and metastatic brain tumors, inflammation and ischemia (insufficient supply of blood to an organ) [154-156],... 

Gastrointestinal 1 secretions J, rate of stomach emptying J, rate of intestinal transit time J, liver volume and blood flow... 

In patients whose maldigestion is difficult to control, other underlying conditions should be considered, such as noncompliance, infections of the gastrointestinal tract, celiac disease, lactose deficiency, inflammatory bowel disease, anatomical abnormalities, diabetes, and liver cirrhosis. This question is complicated by the abundance of small intestinal viscous glycoproteins in cystic fibrosis, prolonged intestinal transit times, which may provoke bacterial overgrowth [104], and absorption of the enzymes in their macromolecular form [105]. 

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