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Gastrointestinal toxicology cell models

BIOMARKERS, CELL MODELS, AND IN VITRO ASSAYS FOR GASTROINTESTINAL TOXICOLOGY... [Pg.227]

Models to identify drug effects on gastrointestinal function should cover gastrointestinal motility, nausea and emesis liability, secretory function (e.g., acidic, ions, hormones), and absorption aspects. Both in vitro and in vivo assessments are available and can be used either in stand-alone SP studies or as specific endpoints integrated into toxicology studies. In addition, novel in sUico tools could also be considered. The choice of approach reflects the focus of a project and may involve isolated cells, organ tissues, and/or whole animals. [Pg.302]

See other pages where Gastrointestinal toxicology cell models is mentioned: [Pg.169]    [Pg.397]    [Pg.358]    [Pg.310]    [Pg.310]   
See also in sourсe #XX -- [ Pg.231 , Pg.232 , Pg.233 , Pg.234 ]



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