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GAG Mimetics

SCHEME 10.16 Synthesis of CS glycomimetic polymers through ROMP. [Pg.257]

The utmost precision of chemical synthesis in defining the length and functionalization patterns ensures a prominent role in GAG acquisition for SAR studies. GAG syntheses remain formidable, but recent advances are instrumental in providing the [Pg.257]

Recently, several new GAGs have been investigated as chiral selectors Dermatan sulfate has been successfully demonstrated to act as an enantiomeric selector for a variety of basic drugs, such as /3-sympatho-mimetics, /3-blockers, and antihypertensives (82). More recently, pentosan polysulfate was also investigated as a chiral selector for tryptophan derivatives and several drugs (83). [Pg.296]

See other pages where GAG Mimetics is mentioned: [Pg.11] [Pg.256] [Pg.217] [Pg.520] [Pg.244] [Pg.82] [Pg.11] [Pg.256] [Pg.217] [Pg.520] [Pg.244] [Pg.82] [Pg.256] [Pg.257] [Pg.279] [Pg.13] [Pg.249] [Pg.251] [Pg.7] [Pg.287]

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GAGs

Gagging

Mimetic

Mimetics