Fungi activity testing

The wide range of micro-organisms found in emulsion paints dictates the use of broad spectrum products. However, many biocides are less active against fungi than bacteria (or vice versa) and it is therefore important to ensure that biocide manufacturers claims are backed up by results of realistic in-use tests. 

Following the first demonstration of the deleterious effect of radiation and ultimately that of chemicals on genetic material, numerous test systems have been used to study the induction of DNA damage, chromosomal aberrations, and mutations. This broad spectrum of activity resulted in the birth of genetic toxicology. The test organisms include prokaryotes (e.g., bacteria, fungi) and eukaryotes (e.g., yeast, fruit flies, plants, mammals). 

Dibromoethane tested positive for mutagenicity with or without metabolic activation in fungi and mammalian cell lines in in vitro assay systems (Brimer et al. 1982 Clive et al. 1979 ... 

Genotoxicity. 1,2-Dibromoethane has been tested for mutagenic activity in a battery of in vitro and in vivo assay systems. It is mutagenic in bacteria, fungi, fruit flies, and cultured mammalian cells (Ames andYanofasky 1971 Barber 1981 Brimeret al. 1982 Crespi etal. 1985 Moriya etal. 1983 ... 

---