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Functional groups methoxy

Other functional groups that are easily differentiated are cyanide (5c =110-120) from isocyanide (5c = 135- 150), thiocyanate (5c =110-120) from isothiocyanate (5c = 125 - 140), cyanate (5c = 105- 120) from isocyanate (5c = 120- 135) and aliphatic C atoms which are bonded to different heteroatoms or substituents (Table 2.2). Thus ether-methoxy generally appears between 5c = 55 and 62, ester-methoxy at 5c = 52 N-methyl generally lies between 5c = 30 and 45 and. S-methyl at about 5c = 25. However, methyl signals at 5c = 20 may also arise from methyl groups attached to C=X or C=C double bonds, e.g. as in acetyl, C//j-CO-. [Pg.12]

The stabilizing role of other functional groups can also be described in resonance terms. Both electron-attracting groups such as carbonyl and cyano and electron-donating groups such as methoxy and dimethylamino have a stabilizing etfect on a radical intermediate at an adjacent carbon. The resonance structures which depict these interactions indicate delocalization of the unpaired electron onto the adjacent substituents ... [Pg.693]

Electron-deficient 1,3-dienes are known to react when heated with metho-xy(aryl)- or methoxy(alkyl)carbene complexes to afford vinylcyclopropane derivatives with high regioselectivity and diastereoselectivity [8a, 24]. Cyclo-propanation of the double bond not bearing the acceptor functional group and... [Pg.66]

Examples of Dienes and Dienophiles. The synthetic value of D-A reactions can be enhanced in various ways. In addition to hydrocarbon dienes, substituted dienes can be used to introduce functional groups into the products. One example that illustrates the versatility of such reagents is l-methoxy-3-trimethylsiloxy-l,3-butadiene... [Pg.487]

In some instances, treatment of polyfunctional benzylic alcohols with acid in the presence of organosilicon hydrides causes multiple functional group transformations to occur simultaneously. This phenomenon is illustrated by the reduction of the secondary benzylic alcohol function and concomitant loss of the methoxymethyl protecting group of 2-(l-hydroxydecyl)-5-methoxy-l-(methoxy-methyleneoxy)naphthalene upon treatment with Et3SiH/TFA in dichloromethane (Eq. 26).167... [Pg.20]

The intermolecular Heck reaction of halopyridines provides an alternative route to functionalized pyridines, circumventing the functional group compatibility problems encountered in other methods. 3-Bromopyridine has often been used as a substrate for the Heck reaction [124-126]. For example, ketone 155 was obtained from the Heck reaction of 3-bromo-2-methoxy-5-chloropyridine (153) with allylic alcohol 154 [125]. The mechanism for such a synthetically useful coupling warrants additional comments oxidative addition of 3-bromopyridine 153 to Pd(0) proceeds as usual to give the palladium intermediate 156. Subsequent insertion of allylic alcohol 154 to 156 gives intermediate 157. Reductive elimination of 157 gives enol 158, which then isomerizes to afford ketone 155 as the ultimate product This tactic is frequently used in the synthesis of ketones from allylic alcohols. [Pg.213]

In 1999, Binet et al.395 published a review on the response of adsorbed molecules to the oxidized/reduced states of ceria. In light of recent infrared studies on ceria, the assignments for OH groups, methoxy species, carbonate species, and formates are highly instructive. The OH and methoxy species have been briefly discussed. Characteristic band assignments of carbonate and formate species are provided below, the latter formed form the dissociative adsorption of formic acid, the reaction of CO with H2-reduced ceria surface, or via selective oxidation of methanol. Formate band intensities were a strong function of the extent of surface reduction of ceria. [Pg.213]

Compounds of type 111 should, in principle, be resolvable into stable enantiomers if the barrier is high enough. However, these compounds do not carry a functional group convenient for resolution. Oki and associates (162) modified one of the methyls in the isopropyl group to make the rotational isomers dia-stereomeric. They prepared 9-(2-methoxy-l-methylethyl)triptycenes (114) and... [Pg.65]

Since the Diels-Alder reaction takes place at high temperatures only, an important requirement of the functional groups is their thermal stability, which in some cases necessitates protection. So far we were able to decorate our polyphenylene dendrimers via this method with various functional groups including methoxy-, amino-, cyano-, halogen-, thiomethyl-, perylenemonoimidyl-, and thiophenyl. [Pg.24]

Capsaicin analogues that differ in only one functional group affect birds and mammals differently. A change from an acidic phenolic hydroxyl group in vanil-lyl acetamide to a methoxy group in veratryl acetamide reverses the effect on starlings and rats. The first was aversive to starlings, but attractive to rats, while the opposite was true for veratryl acetamide (Mason etal., 1991). [Pg.21]

Methyl esters are always the preferred substrates, conversions being lower with, for example, ethyl esters. Functional groups such as nitro, methoxy, alkenyl and pyridyl are compatible with the reaction conditions. Diesters can only be effective if bis-transesterification is desired, when an excess of the alcohol (e.g., 3-5 equiv) is necessary. Methyl acrylate tends to polymerize under the reaction conditions, but the use of an excess of the ester (3-5 equiv) and lower temperatures (-10°C) allows efficient isolation of the required ester. [Pg.208]

Nucleophilic substitution with heteroaryl halides is a particularly useful and important reaction. Due to higher reactivity of heteroaryl halides (e.g. 35, equation 24) in nucleophilic substitution these reactions are widely employed for synthesis of Al-heteroaryl hydroxylamines such as 36. Nucleophilic substitution of halogen or sulfonate functions has been performed at positions 2 and 4 of pyridine , quinoline, pyrimidine , pyridazine, pyrazine, purine and 1,3,5-triazine systems. In highly activated positions nucleophilic substitutions of other than halogen functional groups such as amino or methoxy are also common. [Pg.126]


See other pages where Functional groups methoxy is mentioned: [Pg.362]    [Pg.362]    [Pg.1057]    [Pg.139]    [Pg.217]    [Pg.11]    [Pg.102]    [Pg.27]    [Pg.127]    [Pg.825]    [Pg.108]    [Pg.113]    [Pg.17]    [Pg.212]    [Pg.260]    [Pg.342]    [Pg.1057]    [Pg.13]    [Pg.964]    [Pg.357]    [Pg.7]    [Pg.131]    [Pg.708]    [Pg.74]    [Pg.42]    [Pg.172]    [Pg.532]    [Pg.250]    [Pg.393]    [Pg.1073]    [Pg.67]    [Pg.70]    [Pg.135]    [Pg.123]    [Pg.104]    [Pg.23]    [Pg.50]    [Pg.27]    [Pg.211]    [Pg.367]   
See also in sourсe #XX -- [ Pg.60 , Pg.65 , Pg.101 , Pg.102 , Pg.119 , Pg.120 , Pg.123 , Pg.128 , Pg.139 ]




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Methoxy groups

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